Project CP2: "Recruiting, Assessment, and Biobanking" in the clinical research unit 256 with the title " Mechanisms of Disturbed Emotion Processing in Borderline-Personality Disorder"

Project CP2: "Recruiting, Assessment, and Biobanking" in the clinical research unit 256 with the title " Mechanisms of Disturbed Emotion Processing in Borderline-Personality Disorder" - KFO256 - CP2

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00010146

Enrollment

1054

Registered

2016-03-16

Start date

2012-04-01

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

F60.31 F43.1

Interventions

Group 1: All participants have to do a diagnostic in two steps. First a telephone screening to clear up the in- and exclusion criteria (1 hour), followed by a on-site diagnostic assessment with train

Eligibility

Sex/Gender

All

Age

15 Years to 45 Years

Inclusion criteria

Inclusion criteria: Current Borderline Personality disorder: min. 5 criteria IPDE (International Personality Disorder Examination); Remitted Borderline Personality disorder: max. 3 criteria IPDE about the last 2 years and min. 5 criteria at an earlier time point, as diagnosed by IPDE; Posttraumaticstress Disorder (PTSD): PTSD according to DSM-IV (SCID I); sexual abuse during childhood according to Childhood Trauma Questionnaire (CTQ); Fibromyalgia: Criteria of the American College of Rheumatology (Wolfe et al., 2010); Healthy Controlls: No psychiatric Axis I disorder according life span; no BPD (SCID I and IPSE);

Exclusion criteria

Exclusion criteria: - psychotropic medication - lifetime diagnosis schizophrenia or bipoloar I disorder - substance dependence within two years prior to study, current substance abuse (veryfied by negative urine drug screening) - pregnancy - history of epilepsy, brain trauma, brain tumor, or other significant neurological or medical condition For imaging studies, additionally: - metal implants or electric implants that cannot be removed - claustrophobia

Design outcomes

Primary

Measure	Time frame
The planned outcome is the recruitment and diagnostic assessment of participants as described below. Furthermore biomaterial will be processed and stored for later genetic analyses. Incusion into study occures after positive telephone screening followed by on-site diagnostic assessment with trained psychologists (IPDE, SKIC I) and self ratings (questionnaires: ADHS-SB, AQ, BDI, BIS, BSL-23, CAARS-S:L, CTQ, DERS, FDS, HEXACO, PIV, SCL-90, STAI-G, STAXI, SVV-CL, WURS-k). Period of recruiting: 01.04.2012-31.03.2018. Participant groups: current Borderline-Personality Disorder (age 18-45, female): 267; current Borderline-Personality Disorder (age 15-17, female): 35; current Borderline-Personality Disorder (age 18-45, male): 87; remitted Borderline-Personality Disorder (age 18-45): 85; Fibromyalgia (age 18-45, female): 35; Posttraumatic Stress Disorder (age 18-45, female): 60; Social Anxiety Disorder (age 18-45, female): 40; Autism Spectrum Disorder (age 18-45, female and male): 40; Healthy Controls (age 15-17, female): 35; Healthy Controls (age 18-45, female): 240; Healthy Controls (age 18-45, male) 95;	—

Measure

Time frame

The planned outcome is the recruitment and diagnostic assessment of participants as described below. Furthermore biomaterial will be processed and stored for later genetic analyses. Incusion into study occures after positive telephone screening followed by on-site diagnostic assessment with trained psychologists (IPDE, SKIC I) and self ratings (questionnaires: ADHS-SB, AQ, BDI, BIS, BSL-23, CAARS-S:L, CTQ, DERS, FDS, HEXACO, PIV, SCL-90, STAI-G, STAXI, SVV-CL, WURS-k). Period of recruiting: 01.04.2012-31.03.2018. Participant groups: current Borderline-Personality Disorder (age 18-45, female): 267; current Borderline-Personality Disorder (age 15-17, female): 35; current Borderline-Personality Disorder (age 18-45, male): 87; remitted Borderline-Personality Disorder (age 18-45): 85; Fibromyalgia (age 18-45, female): 35; Posttraumatic Stress Disorder (age 18-45, female): 60; Social Anxiety Disorder (age 18-45, female): 40; Autism Spectrum Disorder (age 18-45, female and male): 40; Healthy Controls (age 15-17, female): 35; Healthy Controls (age 18-45, female): 240; Healthy Controls (age 18-45, male) 95;

—

Secondary

Measure	Time frame
The inter-rater reliability is been verified by quarterly video recordings of all diagnosticians. The videos will be rated by all other diagnosticians to compaire the results. The rating of the following questionnaires will be verified: IPDE, SCID-I	—

Countries

Austria, Germany, Switzerland

Contacts

Public ContactMarija Gligorijevic

Zentralinstitut für Seelische Gesundheit, Universität Heidelberg

marija.gligorijevic@zi-mannheim.de0621/1703-4464

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026