specific biomarkers for chicken breast meat, fibers (inulin, beta.glucan), and egg in healthy female and male volunteers
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: -healthy women and men (age 18-40 years) -BMI <30 kg/m2 -non-smokers -informed consent
Exclusion criteria
Exclusion criteria: -smokers --gastro-intestinal diseases resulting in malabsorption, digestion -diseases impairing metabolism and excretion -chronic illness -acute infection -intake of antibiotics in the last 6 months -regular intake of medication (exception: oral contraceptive) -pregnant and lactating women -known allergies or intolerance to tested foods
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Analysis of metabolites in plasma and urine using LC-MS/MS, GCxGC-MS, and NMR after a single consumption of chickenbreast (100g and 200g), fibers (inulin and beta-glucan), and egg compared to controlfood (for chickenbreast and egg:rice; for fibers:toastbred). Timepoints for taking blood samples are 0, 1,2,4,6,12,and 24 hours. Timepoints for urinesampling are 0-1h, 1-2h, 2-4h, 4-6h, 6-12h, 12-24h, 48h. | — |
Countries
Germany
Contacts
ZIEL Institute for Food and Health Ernährungsmedizinan der Technischen Universität München