Mid-German Sepsis Cohort

Conditions

R65.1 R57.2

Carolin Fleischmann-Struzek, Miriam Kesselmeier, Dominique Ouart, Christiane S. Hartog, Michael Bauer et al. (24 authors)

BMJ Open2021-03-0112 citations

10.1136/bmjopen-2020-043352

A patient cohort on long-term sequelae of sepsis survivors: study protocol of the Mid-German Sepsis Cohort

André Scherag, Christiane S. Hartog, Carolin Fleischmann-Struzek, Dominique Ouart, Franziska Hoffmann et al. (14 authors)

BMJ Open2017-08-0120 citations

10.1136/bmjopen-2017-016827

Internet-based cognitive–behavioural writing therapy for reducing post-traumatic stress after intensive care for sepsis in patients and their spouses (REPAIR): study protocol for a randomised-controlled trial

Romina Gawlytta, Helen Niemeyer, Maria Böttche, André Scherag, Christine Knaevelsrud et al. (6 authors)

BMJ Open2017-02-0135 citations

10.1136/bmjopen-2016-014363

Interventions

Group 1: After ICU discharge, patients will be surveyed for as long as possible in regular intervals: 3 months, 6 months, 12 months, 24 months, 36 months, 48 months und 60 months after ICU discharge.

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: ICU-treated severe sepsis or septic shock

Exclusion criteria

Exclusion criteria: previous participation in the MSC-study

Design outcomes

Primary

Measure	Time frame
Functional ability as defined by six activities of daily living (ADLs: walking, dressing, bathing, eating, etc.) or five instrumental activities of daily living (IADLs: preparing a hot meal, shopping for groceries, making telephone calls, etc.); taken together as "activities of daily living" (ADL) and "instrumental activities of daily living" (IADL), displayed in the so-called “Frührehabilitations-Barthel-Index (FRB)” and Barthel index, respectively. Analyses are done to detect individual changes in total score between ICU discharge and current follow up: 3 months, 6 months, 12 months, 24 months, 36 months, 48 months und 60 months after ICU discharge.	—

Measure

Time frame

Functional ability as defined by six activities of daily living (ADLs: walking, dressing, bathing, eating, etc.) or five instrumental activities of daily living (IADLs: preparing a hot meal, shopping for groceries, making telephone calls, etc.); taken together as "activities of daily living" (ADL) and "instrumental activities of daily living" (IADL), displayed in the so-called “Frührehabilitations-Barthel-Index (FRB)” and Barthel index, respectively. Analyses are done to detect individual changes in total score between ICU discharge and current follow up: 3 months, 6 months, 12 months, 24 months, 36 months, 48 months und 60 months after ICU discharge.

—

Secondary

Measure	Time frame
Overall and cause-specific survival, number of recurrent infections, health-related quality of life (EQ-5D-3L), cognitive deficiency score (telefon-MOCA, IQCODE), weight, return to work, posttraumatic stress (PTSS-10), anxiety and depression (PHQ-9). Inquiry at 3 months, 6 months, 12 months, 24 months, 36 months, 48 months und 60 months after ICU discharge - via interview/questionnaires.	—

Countries

Germany

Contacts

Public ContactAndré Scherag

Universitätsklinikum Jena, Center for Sepsis Control and Care (CSCC) & Institut für Medizinische Statistik, Informatik und Datenwissenschaften (IMSID)

andre.scherag@med.uni-jena.de+49-(0)36419396954

Outcome results

None listed