Do Antibacterial skin sutures reduce surgical site infections after open abdominal surgery?

Do Antibacterial skin sutures reduce surgical site infections after open abdominal surgery? - DASSReSSiAS-Trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00010047

Enrollment

364

Registered

2017-01-05

Start date

2016-02-11

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

T81.4

Interventions

Group 1: wound closure with a continuous subcuticular suture with a absorbable, monofile, non-coated suture (Monocryl 4x0) Group 2: wound closure with an absorbable, monofile, triclosan-coated suture

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: planned laparotomy, elucidation

Exclusion criteria

Exclusion criteria: emergency, allergy to the suture, participation to a competing study

Design outcomes

Primary

Measure	Time frame
The primary outcome is the occurrence of SSI defined by the CDC guidelines1 as superficial or deep incisional or either organ space infection. SSI is measured in incisional wounds after open abdominal surgery with skin suture with triclosan-coated poliglecaprone 25 (Monocryl plus; Ethicon GmbH, Norderstedt, Germany) in comparison with normal poliglecaprone 25 (Monocryl; Ethicon GmbH, Norderstedt, Germany) within 30 days after surgery	—

Measure

Time frame

The primary outcome is the occurrence of SSI defined by the CDC guidelines1 as superficial or deep incisional or either organ space infection. SSI is measured in incisional wounds after open abdominal surgery with skin suture with triclosan-coated poliglecaprone 25 (Monocryl plus; Ethicon GmbH, Norderstedt, Germany) in comparison with normal poliglecaprone 25 (Monocryl; Ethicon GmbH, Norderstedt, Germany) within 30 days after surgery

—

Secondary

Measure	Time frame
Secondary endpoints of this study are wound dehiscence and re-operation rate due to wound dehiscence, all-cause 30-day mortality and length of hospital stay.	—

Countries

Germany

Contacts

Public ContactDaniel Matz

AGAPLESION Diakonieklinikum Rotenburg (Wümme)Klinik für Allgemein-, Viszeral- und Thoraxchirurgie

d.matz@diako-online.de04261772757

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 21, 2026