Robotic-assisted radical prostatectomy in steep Trendelenburg position - cerebral perfusion and oxygenation in patients with impaired cerebral autoregulation and risk of postoperative cognitive deficits

Conditions

F06.7 F05.8

Ursula Kahl, Cornelius Rademacher, Ulrich Harler, Neelke Juilfs, Hans O. Pinnschmidt et al. (9 authors)

Journal of Clinical Monitoring and Computing2021-04-1514 citations

Kahl U, Callsen S, Beck S, Pinnschmidt H, von Breunig F, Haese A, Graefen M, Zöllner C, Fischer M.

2021-02-2510 citations

Comparing the effect of positioning on cerebral autoregulation during radical prostatectomy: a prospective observational study.

Beck S, Ragab H, Hoop D, Meßner-Schmitt A, Rademacher C, Kahl U, von Breunig F, Haese A, Graefen M, Zöllner C, Fischer M.

2020-06-208 citations

10.1007/s10877-020-00549-0

Postanesthesia care unit delirium following robot‐assisted vs open retropubic radical prostatectomy: A prospective observational study

Stefanie Beck, Dennis Hoop, Haissam Ragab, Cornelius Rademacher, Aurélie Meßner-Schmitt et al. (10 authors)

International Journal of Medical Robotics and Computer Assisted Surgery2020-02-1912 citations

10.1002/rcs.2094

Interventions

Group 1: measurement of cerebrovascular autoregulation (intraoperative) and assessment of postoperative cognitive deficits in patients with robotic-assisted radical prostatectomy (robot-assisted, lapa

Eligibility

Sex/Gender

Male

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: >18 years, ASA classification I-IV, written informed consent, excellent (German) language skills in order to undergo the neuropsychological testing

Exclusion criteria

Exclusion criteria: history of cerebrovascular disease, intracranial pathology, dementia, ASA >=V (American Society of Anesthesiology physical status classification system)

Design outcomes

Primary

Measure	Time frame
1) Cerebral autoregulation (cerebral oxygenation index, intraoperative measurement), 2) postoperative cognitive dysfunction (pre- and postoperative assessment: California Verbal Learning Test, grooved pegboard test, Trail Making Test A/B, digit span test)	—

Secondary

Measure	Time frame
postoperative delirium (CAM-ICU), self-assessed cognitive function, blood pressure variability, hemodynamic parameters	—

Countries

Germany

Contacts

Public ContactMarlene Fischer

Universitätsklinikum Hamburg-Eppendorf, Klinik für Anästhesiologie

studie_anaesthesie@outlook.com040 7410 52415

Outcome results

None listed