Regional ventilation distribution in patients with severe emphysema determined by electrical impedance tomography before and after endoscopic valve therapy for lung volume reduction

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00009991

Enrollment

Registered

2017-01-24

Start date

2017-02-01

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

J43 J44

Interventions

Group 1: Electical impedance tomography before and after endoscopic valve therapy in patients with severe emphysema

Eligibility

Sex/Gender

All

Age

18 Years to 80 Years

Inclusion criteria

Inclusion criteria: - Written informed consent - already authorised indication and information to patient about the endoscopic valve therapy - Age = 18 and = 80 years - COPD with emphysema requiring intervention

Exclusion criteria

Exclusion criteria: - Withdrawal of informed consent - Severe obesity - Chest deformities - Severe instable comorbidities - Severe pulmonary hypertension - Post lung resection condition - Suspected tumour in the lungs - Suspected pulmonary adhesions, scarring and bronchiectasis - Collateral ventilation - Incapacitated patients

Design outcomes

Primary

Measure	Time frame
Detection of the possible regional change in ventilation distribution after endoscopic valve therapy using electrical imepdance tomography (EIT) in patients with emphysema	—

Secondary

Measure	Time frame
Determination of regional heterogeneity of ventilation distribution after endoscopic valve therapy using new developped regional EIT-parameters in patients with emphysema	—

Countries

Germany

Contacts

Public ContactLorenz Balke

Klinik für Innere Medizin I, Abteilung Pneumologie, Universitätsklinikum Schleswig-Holstein, Campus Kiel

lorenz.balke@uksh.de04315971393

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026