Quantitative fMRI-imaging study of cerebral pathways during movement to music in patients with Parkinson’s Disease

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00009986

Enrollment

Registered

2016-04-05

Start date

2016-10-20

Completion date

Unknown

Last updated

2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

G20

Interventions

Group 1: Parkinson's patients: opening and closing of the fist as a simplification of dance to 1.) rhythm, to 2.) music and 3.) in silence during fMRI imaging. Group 2: Healthy controls: opening and c

Eligibility

Sex/Gender

All

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Patients: Patients over 18 with idiopathic Parkinson's Syndrome of the akinetic-rigid type. Signed consent. Healthy controls: Neurologically healthy individuals matched for age, sex and dominant hand. Signed consent.

Exclusion criteria

Exclusion criteria: Patients: (i) Contraindications for MRI scans (see also MRI information sheet), (ii) inappropriate physical conditions which prohibit a 30 - 45 minute MRI scan, (iii) brain pathologies such as history of stroke, severe cerbral microangiopathy, tumors, inflammation, (iv) pregnancy, (v) patients with Deep Brain Stimulation. Healthy controls: (i) Contraindications for MRI scans (see also MRI information sheet), (ii) inappropriate physical conditions which prohibit a 30 - 45 minute MRI scan, (iii) brain pathologies such as history of stroke, severe cerbral microangiopathy, tumors, inflammation, (iv) pregnancy, (v) Parkinson's Disease vi) Parkinsonoid symptoms.

Design outcomes

Primary

Measure	Time frame
Assessment of difference in cerebral activity during movement to music, to rhythm and in silence in people with Parkinson's Disease. These differences in cerebral activity result in changes to the fMRI-signal which can be measured.	—

Secondary

Measure	Time frame
The differences in cerebral activity to rhythm, music and in silence correlate with the patient's movement to rhythm, music and in silence, respectively. The amplitude and frequency of the movement (i.e. the opening and closing of the fist) is measured via a pressure sensor which the patient/ healthy control holds in their hand throughout the entire procedure.	—

Countries

Germany

Contacts

Public ContactVolker Arnd Coenen

Klinik für Neurochirurgie

volker.coenen@uniklinik-freiburg.de0761 270-50010/-50020

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Apr 4, 2026