Whole body vibration to preserve physical capacity during allogeneic haematopoietic cell transplantation

Whole body vibration to preserve physical capacity during allogeneic haematopoietic cell transplantation - alloViTra

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00009918

Enrollment

Registered

2016-03-03

Start date

2016-04-04

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

all patients during allogenic stemcelltransplantation C81-C96 D46

Interventions

Group 1: Whole body vibration training performed on a side-alternating oscillation platform (five times/ week, 20-25 min per training session) Group 2: Intervention consists of standard inpatient care

Eligibility

Sex/Gender

All

Age

16 Years to 80 Years

Inclusion criteria

Inclusion criteria: All patients eligible for alloHCT. All patients able to perform cardiopulmonary exercise test. Signed informed consent.

Exclusion criteria

Exclusion criteria: Instable bone metastases, epilepsy, endoprothesis in knee or hip, severe heart disease NYHA III-IV, pacemaker

Design outcomes

Primary

Measure	Time frame
phyiscal performance (VO2peak) at the time of discharge (T1)	—

Secondary

Measure	Time frame
- Physical performance (VO2peak) measured during cardiopulmonary exercise test on cycle ergometer 180 days after alloHCT - mobility und strength [cm;s;F] force platform (Leonardo Mechanograph®) -Maximum strength: maximum voluntary contraction (MVC) of knee extension and flexion (Contrex®) - gait speed and gait variability (Moticon, openGo®) - Thickness of the quadriceps femoris muscle [cm] Ultrasonography at midpoint of the thigh -Body composition (fat-free mass, body cell mass, phase angle) [(°; %)] - qualitiy of life and fatigue (EORTC QLQ C30; EORTC-QLQ_HDC29; MFI) -physical activity before and after diagnosis - FES-I questionnaire -Transplant-specific outcomes	—

Measure

Time frame

- Physical performance (VO2peak) measured during cardiopulmonary exercise test on cycle ergometer 180 days after alloHCT - mobility und strength [cm;s;F] force platform (Leonardo Mechanograph®) -Maximum strength: maximum voluntary contraction (MVC) of knee extension and flexion (Contrex®) - gait speed and gait variability (Moticon, openGo®) - Thickness of the quadriceps femoris muscle [cm] Ultrasonography at midpoint of the thigh -Body composition (fat-free mass, body cell mass, phase angle) [(°; %)] - qualitiy of life and fatigue (EORTC QLQ C30; EORTC-QLQ_HDC29; MFI) -physical activity before and after diagnosis - FES-I questionnaire -Transplant-specific outcomes

—

Countries

Germany

Contacts

Public ContactAntonia Pahl

Universitätsklinik Freiburg, Department Innere Medizin, Klinik für Innere Medizin I, Schwerpunkt Hämatologie, Onkologie und Stammzelltransplantation

antonia.pahl@uniklinik-freiburg.de076127073240

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026