Cytokine expression patterns in patients with traumatic Spinal Cord Injury

Cytokine expression patterns in patients with traumatic Spinal Cord Injury - SCI cytokine study

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00009917

Enrollment

130

Registered

2016-03-23

Start date

2012-07-25

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

T09.3 G95.9

Interventions

Group 1: Patients with traumatic Spinal Cord Injury fulfilling the inclusion criteria are included in the study. According to the Neurological Remission patients are divided in two Groups (G1=Patients

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patient with acute traumatic Spinal Cord Injury

Exclusion criteria

Exclusion criteria: non-traumatic spinal cord injury, traumatic brain injury (TBI), severe abdominal trauma, traumatic amputation of extremities and coma. Participants were given neither methylprednisolone sodium succinate (MPSS) nor nonsteroidal anti-inflammatory drugs (NSAIDs) during study participation.

Design outcomes

Primary

Measure	Time frame
ASIA score* after 3 months *This is a system of tests used to define and describe the extent and severity of a patient’s spinal cord injury and help determine future rehabilitation and recovery needs. The patient’s grade is based on how much sensation he or she can feel at multiple points on the body, as well as tests of motor function. ASIA (ASIA Impairment Scale) Grade A Complete lack of motor and sensory function below the level of injury (including the anal area) Grade B Some sensation below the level of the injury (including anal sensation) Grade C Some muscle movement is spared below the level of injury, but 50 percent of the muscles below the level of injury cannot move against gravity. Grade D Most (more than 50 percent) of the muscles that are spared below the level of injury are strong enough to move against gravity. Grade E All neurologic function has returned.	—

Measure

Time frame

ASIA score* after 3 months *This is a system of tests used to define and describe the extent and severity of a patient’s spinal cord injury and help determine future rehabilitation and recovery needs. The patient’s grade is based on how much sensation he or she can feel at multiple points on the body, as well as tests of motor function. ASIA (ASIA Impairment Scale) Grade A Complete lack of motor and sensory function below the level of injury (including the anal area) Grade B Some sensation below the level of the injury (including anal sensation) Grade C Some muscle movement is spared below the level of injury, but 50 percent of the muscles below the level of injury cannot move against gravity. Grade D Most (more than 50 percent) of the muscles that are spared below the level of injury are strong enough to move against gravity. Grade E All neurologic function has returned.

—

Secondary

Measure	Time frame
Neurological Remission according to ASIA Score after 3 months (Examinating wheather the patient had a neurological improvement or not)	—

Countries

Germany

Contacts

Public ContactRaban Heller

HTRG Heidelberg Trauma Research GroupDepartment für Orthopädie, Unfallchirurgie und Paraplegiologie

raban.heller@med.uni-heidelberg.de+49 (0)6221 56 35353

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026