O36.5 O14.1 O24.4
Conditions
Interventions
Group 1: Pregnant women with FGR with and without diabetes or preeclampsia will be included into the study. Maternal blood, umbilical cord blood, and placental and umbilical cord tissue will be sample
Sponsors
Universitätsklinikum Schleswig-Holstein, Campus Kiel, Klinik für Gynäkologie und Geburtshilfe
Eligibility
Sex/Gender
Female
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Case group: pregnant women with suspected FGR with / without preeclampsia or diabetes. control group: pregnant women in which FGR has been excluded with / without preeclampsia or diabetes.
Exclusion criteria
Exclusion criteria: fetal anomalies, abnormal fetal karyotype, patients with clinical or biochemical signs of infection, positive TORCH screening results, or other severe maternal metabolic disorders, and the patient's withdrawal from the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Study aim: In the study we test the hypothesis that cholesterol-transport processes are involved in the regulation of placental and fetal angiogenesis in FGR. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary study aim: In the study we test the hypothesis that a disturbed cholesterol transport is involved in the development cardiovascular diseases later in life. | — |
Countries
Germany
Contacts
Public ContactUlrich Pecks
Universitätsklinikum Schleswig-HolsteinCampus KielKlinik für Gynäkologie und Geburtshilfe
Outcome results
None listed