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Standardized training for improvement of the musculoskeletal unit and for prevention of falls and fracture in the elderly: a prospective randomized controlled trial. Age adjusted impact strength and enDurance training in Osteoporotic patients - Novel structu-red Intervention in Seniors (the Rostocker ADONIS-Trial)

Standardized training for improvement of the musculoskeletal unit and for prevention of falls and fracture in the elderly: a prospective randomized controlled trial. Age adjusted impact strength and enDurance training in Osteoporotic patients - Novel structu-red Intervention in Seniors (the Rostocker ADONIS-Trial) - ADONIS

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
DRKS
Registry ID
DRKS00009890
Enrollment
30
Registered
2016-01-22
Start date
2012-10-15
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

M80-M85

Interventions

Group 1: training of strength and endurance (step aerobics) two times a week, 45 min per session medication as prescribed Group 2: no intervention

Sponsors

Klinik für Unfall-, Hand-, und Wiederherstellungschirurgie
Lead Sponsor

Eligibility

Sex/Gender
All
Age
65 Years to No maximum

Inclusion criteria

Inclusion criteria: age = 65 years, T-score = - 2.5 standard deviation at the lumbar spine and/or femoral neck (measurement of BMD at max. 36 months prior to enrolment) or a history of osteoporotic fractures, walking speed = 0.8 m·s-1, chair rising test = 10 s, body mass index = 20 kg/m2, increased risk of falls and fractures, i.e. at time of enrolment at least one fall during the last 12 months.

Exclusion criteria

Exclusion criteria: active participation in a strength and/or endurance training during a 24-months period prior to enrolment, sports activity = two times a week, cardiac insufficiency, cardiac pacemaker, chronic renal failure, non-curative treated tumours, systemic application of corticosteroids, peripheral arterial occlusive disease, poor mobility, i.e. walking more than 5 min not possible, osteoarthritis, rheumatism and/or severely impaired balance, planed absence of more than two weeks during the study period

Design outcomes

Primary

MeasureTime frame
feasibility of the training acceptance of intensity and frequence Questionaires (QUALEFFO-41, FES-1) at time of enrollment (baseline) and after 3 and 6 months of training

Secondary

MeasureTime frame
improvement of muscular function (power) by 10% within 6 months of training Questionaires, assessment of endurance and power at time of enrollment (baseline) and after 3 and 6 months of training

Countries

Germany

Contacts

Public ContactThomas Mittlmeier

Klinik für Unfall-, Hand-, und Wiederherstellungschirurgie

thomas.mittlmeier@med.uni-rostock.de0381 - 4 94 6051

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026