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Structure and function of the hippocampal CA2 region in temporal lobe epilepsy

Structure and function of the hippocampal CA2 region in temporal lobe epilepsy

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
DRKS
Registry ID
DRKS00009879
Enrollment
60
Registered
2016-01-18
Start date
2015-05-19
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Temporal lob epilepsy G40.09

Interventions

Group 1: Observation group: patients with temporal lobe epilepsy. Histological and physiological investigation of specimens

Sponsors

Experimentelle Epilepsieforschung, Neurozentrum
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Existence of a pharmacoresistant temporal lobe epilepsy with surgical resection of the hippocampus

Exclusion criteria

Exclusion criteria: Patient does not allow the transfer of tissue for research

Design outcomes

Primary

MeasureTime frame
Clarifying the physiological properties of CA2 neurons in single cell physiology Quantitative knowledge on the survival numbers of CA2 neurons with histological / immunocytochemical methods Full knowledge of synaptic connectvity of CA2 neurons with histological /immunocytochemical methods

Countries

Germany

Contacts

Public ContactUte Häussler

Experimentelle Epilepsieforschung, Neurozentrum

ute.haeussler@uniklinik-freiburg.de0761 270 54450

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026