K05 K02
Conditions
Interventions
Group 1: A test cycle begins with an examination on day 0, a four -day rinsing phase, and an examination on day 4 with a subsequent 9-day wash-out phase. In the rinsing phase the participant should w
Sponsors
Klinik für Präventivzahnmedizin, Parodontologie und Kariologie (PPK)Zentrum für ZahnmedizinUniversität Zürich
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: -10 female + 10 male subjects (stratified study), in the age of at least 18 years - either full dentition or partial missing (at least 3 adjacent posterior teeth with no more than 2 approximate and/or 2 buccal restorations on both maxilla sides without buccal dental veneer) - caries-free denture - Gingiva free of inflammation - interdental brushes should be applicable - signed information sheet - subjects should be able to perform the study plan
Exclusion criteria
Exclusion criteria: - artificial dentition - pregnant and lactating women - patients participating in any other clinical trial within the last 3 months prior to enrollment - lack of compliance (adherence) - patients taking antibiotics during study - alcoholic-, drug- or medicaments abuse - patients with known sensibilities against ingredients of the used dentifrices - strong smoker (more than 10 cigarettes per day)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| After the preparation phase , the testing phase can be started with the test toothpastes (only high responder) . Here, baseline and post-treatment measurements will be compared of the amount of bacteria, degree of inflammation, and the amount of plaque in dependence of the respective test toothpastes. Baseline measurements are taken on day 0, post-treatment measurements in each cycle (4 in total) on day 4. In each case, a clinical examination is carried out . | — |
Secondary
| Measure | Time frame |
|---|---|
| The cleaning effect of the differently shaped interdental brushes will be examined in the preparation phase . In addition, so-called high responders are included in the study . Clinical examinations (measurements) will be performed on day 0 and day 4 (bacteria load, degree of inflammation of the gums , probing depth) . | — |
Countries
Switzerland
Contacts
Public ContactPune Nina Tawakoli
Universität Zürich, Zentrum für Zahnmedizin, Klinik für Präventive Zahnmedizin, Parosontologie und Kariologie
Outcome results
None listed