Brain metabolite changes in MR-Spectroscopy in patients with relapsing-remitting and secondary progressive Multiple Sclerosis: two years follow up study

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00009807

Enrollment

Registered

2016-01-04

Start date

2005-12-14

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

G35.9

Interventions

Group 1: changes in metabolite concentration in MR-Spectroscopy in patients with relapsing-remitting Multiple Sclerosis Group 2: changes in metabolite concentration in MR-Spectroscopy in patients with

Eligibility

Sex/Gender

All

Age

18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Patients were classified according to clinical course as having either recurrent relapses or secondary progressive disease course over a maximum period of two years prior to inclusion

Exclusion criteria

Exclusion criteria: cardiac Pacemaker, metal implants, Allergie to contrast agent

Design outcomes

Primary

Measure	Time frame
Timepoint of the disease with the most prominent tNAA reduction in MRS	—

Secondary

Measure	Time frame
Korrelation of metabolite concentration with disability	—

Countries

Germany

Contacts

Public ContactKatharina Hein

Abteilung Neurologie

k.hein@uni-goettingen.de05513966603

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026