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Surgical management of the axilla in primary systemic treatment of breast cancer

Surgical management of the axilla in primary systemic treatment of breast cancer

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
DRKS
Registry ID
DRKS00009793
Enrollment
30
Registered
2015-12-18
Start date
2016-01-04
Completion date
Unknown
Last updated
2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

C50

Interventions

Group 1: Before starting primary chemotherapy suspicious axillary lymphnodes will be marked by a clip (HYDROMARK)

Sponsors

Universitätsfrauenklinik am Klinikum Südstadt
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: all patients diagnosed with invasive breast cancer (c/iT1-3, uni- or bilateral) at the university of rostock, who receive a primary systemic treatment and present with clinically/sonographically suspicious ipsilateral axillary lymphnodes (c/iN+) without distant metastases

Exclusion criteria

Exclusion criteria: male patients, pregnancy, age <18 years, T4-tumors, distant metastases (M1)

Design outcomes

Primary

MeasureTime frame
concordance of primary minimal-invasive histologically proven suspicious axillary, clipmarked lymphnodes and sentinel lymphnodes after primary systemic treatment work measurement: surgery

Secondary

MeasureTime frame
-creation of an oncologically safe concept to reduce axillary surgical radicalness after primary sytemic treatment in breast cancer patients with suspicious ipsilateral lymphnodes -rate of detection of axillary sentinel nodes after primary systemic treatment -predicitve value of the clipmarked lymphnode for metastatic disease in further lymphnodes after primary systemic treatment -adverse events caused by clipmarking lymphnodes

Countries

Germany

Contacts

Public ContactSteffi Hartmann

Universitätsfrauenklinik am Klinikum Südstadt

steffi.hartmann@kliniksued-rostock.de0381/44014500

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Jun 5, 2026