Postmortem Asservation of pericardial tissue to determine the mechanical characteristics in the development of TEMPHUS ("Temporary, mechanical cardiac support system")

Postmortem Asservation of pericardial tissue to determine the mechanical characteristics in the development of TEMPHUS ("Temporary, mechanical cardiac support system") - TEMPHUS Pericardium

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00009789

Enrollment

Registered

2015-12-14

Start date

2015-10-25

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Multiple Organ Failure Syndrome (septic and non septic)

Interventions

Group 1: Harvesting of a part of the pericardial tissue as part of a necropsy. Afterwards experiments with determination of endpoints.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: deceased, critical ill patients; surviving dependants gave their consent to a necropsy

Exclusion criteria

Exclusion criteria: Known pericardial disease (exception: isolated serous pericardial effusion)

Design outcomes

Primary

Measure	Time frame
Calculation of the variance of the modulus of elasticity E=?s/?e	—

Secondary

Measure	Time frame
Mechanical characteristics (in primary stretching): maximum tearing strength [N / mm²] or pull force [N]; maximum extensibility [mm / mm]; Behavior after the linear region Mechanical characteristics (after cyclic stretching): maximum tensile strength [N / mm²] or pull force [N]; maximum extensibility [mm / mm]; Modulus of elasticity (?s / ?e); Behavior after the linear region Basic technical data at rest: Weight of tissue [mg]; Thickness of the tissue [mm]; macroscopic abnormalities.	—

Measure

Time frame

Mechanical characteristics (in primary stretching): maximum tearing strength [N / mm²] or pull force [N]; maximum extensibility [mm / mm]; Behavior after the linear region Mechanical characteristics (after cyclic stretching): maximum tensile strength [N / mm²] or pull force [N]; maximum extensibility [mm / mm]; Modulus of elasticity (?s / ?e); Behavior after the linear region Basic technical data at rest: Weight of tissue [mg]; Thickness of the tissue [mm]; macroscopic abnormalities.

—

Countries

Germany

Contacts

Public ContactJochen Schröder

Universitätsklinikum Halle (Saale)Klinik für Innere Medizin III

jochen.schroeder@uk-halle.de0345 557 2601

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026