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Effect of an untreated vitamin D deficiency on depressive symptoms in child and adolescent psychiatric patients – a randomized controlled trial.

Effect of an untreated vitamin D deficiency on depressive symptoms in child and adolescent psychiatric patients – a randomized controlled trial.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
DRKS
Registry ID
DRKS00009758
Enrollment
200
Registered
2016-06-16
Start date
2016-06-15
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

We do not include any specific psychiatric diagnosis. We include all inpatients or day patients at admission in the Department of Psychiatry, Psychotherapy and Psychosomatics of the University Duisburg-Essen (see inclusion criteria). E55

Interventions

Group 1: Vitamin D supplementation, 2640 IE Vitamin D q.d. ( = 3 tablets Vitamin D à 880 IE in the morning/ day) based on the current practice of the pediatric endocrinologists in chronically ill chil

Sponsors

Universitätsklinikum Essen AöR; Universität Duisburg-Essen, Campus Essen – Med. Fakultät –
Lead Sponsor

Eligibility

Sex/Gender
All
Age
11 Years to 18 Years

Inclusion criteria

Inclusion criteria: In- or day patient child- and adolescent psychiatric admission, age: 11-18.9 years, BDI-II score > 13, 25(OH)-vitami D level < 30nmol/L (12 ng/ml), written informed consent of children/adolescents and their parents.

Exclusion criteria

Exclusion criteria: Current severe somatic disease, hypocalcemia, parathormon (Plasma) > 130ng/ml, IQ < 70, contraindication or refusal of a vitamin D supplementation.

Design outcomes

Primary

MeasureTime frame
Depression score measured via BDI-II after 28 days

Secondary

MeasureTime frame
25(OH)-Vitamin D serum level after 28 days; impulsiveness measured via Barratt Impulsiveness Scale (BIS-11) after 28 days, depression score measured via DISYPS-II depression questionnaire (for parents and children) after 28 days

Countries

Germany

Contacts

Public ContactManuel Föcker

Klinik für Kinder- und Jugendpsychiatrie,-psychosomatik und -psychotherapie, Universitätsklinikum (UKM) Münster

manuel.foecker@ukmuenster.de0251 83 53544

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 24, 2026