The impact of weight reduction on brain's energy homeostasis

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00009754

Enrollment

Registered

2016-03-03

Start date

2014-01-01

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Overweight , obesity E66.00 E66.01 E66.02

Interventions

Group 1: Each subject was tested before and after weight loss during 14 days of body weight loss. Blood parameters (glucose, insulin, C-peptide, ephinephrine, norephinephrine, cortisol) and cerebral

Eligibility

Sex/Gender

All

Age

18 Years to 35 Years

Inclusion criteria

Inclusion criteria: Body mass index >30

Exclusion criteria

Exclusion criteria: Body mass index < 30, acute or chronic physical and mental illness, current medication

Design outcomes

Primary

Measure	Time frame
Cerebral energy content before and after weight loss (14 days). Cerebral energy content is determined by imaging (31 Phosphorus magnetic resonance spectroscopy): Before body weight loss (baseline) and after 14 days.	—

Secondary

Measure	Time frame
Metabolic parameters (glucose, insulin, C-peptide, cortisol, ephinephrine, norephinephrine) before and after weight loss.	—

Countries

Germany

Contacts

Public ContactEwelina Kinga Wardzinski

Sektion für PsychoneurobiologieUniversität Lübeck

wardzinski at pnb.uni-luebeck.de0451 500 6342

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026