Neurochemical Imaging and Mapping of Excitatory and Inhibitory Neurometabolites in Adolescents with Autism Spectrum Disorder

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00009750

Enrollment

Registered

2015-12-16

Start date

2015-12-16

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

F84

Interventions

Group 1: In Youths older than 13 and younger than 18 with diagnosed autism-spectrum-disorder (with the above listed in- and exclusion criteria), neurometabolites will be measured via MR-spectroscopy

Eligibility

Sex/Gender

All

Age

14 Years to 17 Years

Inclusion criteria

Inclusion criteria: Diagnosis of an autism-spectrum-disorder; IQ = 85; otherwise healthy subjects

Exclusion criteria

Exclusion criteria: Further psychiatric, neurologic or internistic disorders that could influence concentrations of neurometabolites. Excessive consumption of alcohol or consumption of illegal drugs in the past 6 months. An IQ below 85. No consent to be informed of possible random MRI-findings.

Design outcomes

Primary

Measure	Time frame
Aim of the study is the measurement and evaluation of neurometabolites concentration in youths with autism-spectrum-disorder and control subjects of the same age, as well as analyzing possible correlations between the metabolites concentration and the severity of the autistic impairments	—

Countries

Germany

Contacts

Public ContactKai Krüger

Universität Freiburg

kai.krueger@uniklinik-freiburg.de00491789832231

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026