M81
Conditions
Interventions
Group 1: -Screening: Examination with control of the inclusion and exclusion criteria with help
of history, DEXA, clinical examination and blood testing
-U1: Initial examination with re-examination of
Sponsors
Institut für Sport und Sportwissenschaft
Eligibility
Sex/Gender
Female
Age
45 Years to 80 Years
Inclusion criteria
Inclusion criteria: -Menopause (last regular bleeding 12 months ago) Osteopenia (-2.5 =T value = -1) or (pre-) clinical osteoporosis T value> 2.5 -no serious diseases -stable weight and nutritional behavior - no Contraindication against protein-rich supplementary nutrition or supplements
Exclusion criteria
Exclusion criteria: - Effective drug therapy of osteoporosis in the last 12 months (Bisphosphonate / SERM or similar) - severe osteoporosis requiring treatment, with impending invalidity or a high degree of fracture risk -serve systematic disease of the rheumatic form -allergies against collagen or other proteins -clear secondary cause of osteoporosis with continuity of the cause (drugs, endocrinological disorders) Malignant diseases (relapse-free 1.5 mg / dL], liver [transaminases> 2 times the norm)]
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Changes in the bone density (T value) after a 12-month intake of 5 g collagen peptides compared to placebo examined by DEXA (Dual Energy X-Ray Absorptiometry) | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary target variables are changes in the bone biomarker procollagen I N-terminal propeptide (P1NP) and the bone resorption marker collagen type I C-telopeptide (CTX I) in the serum after the 12-month intervention phase. The secondary target variables also include the extent to which the administration of 2.5 g collagen peptides to the bone mass (measured bey DEXA) has an effect | — |
Countries
Germany
Contacts
Public ContactDaniel König
Institut für Sport und Sportwissenschaft
Outcome results
None listed