Incidence and extent of a systemic inflammatory response in patients after successful cardiopulmonary resuscitation

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00009684

Enrollment

100

Registered

2015-11-27

Start date

2010-09-21

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

I46.0

Interventions

Group 1: Blood samples from patients after cardiac arrest with successful resuscitation Group 2: Blood samples from patients with coronary artery disease without acute myocardial infarction

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Cardiac arrest with successful resuscitation; Coronary artery disease without acute myocardial infarction

Exclusion criteria

Exclusion criteria: Preexisting acute- or chronic-inflammatory diseases; Preexisting acute- or chronic-infectious diseases; Multiple organ dysfunction syndrome; Immunosuppressive medication

Design outcomes

Primary

Measure	Time frame
Quantitative analysis of peripheral blood leucocyte subclasses; Expression of markers of antigen presentation; Leucocyte response to activation by stimulatory agents; Leucocyte and whole blood expression of markers of innate immunity inflammatory signaling, including toll-like receptor and inflammasome signaling; Single blood sample from control group; Sequential blood sampling in patients in the first hours after survived cardiac arrest as well as 1 day and 2 days after resuscitation;	—

Measure

Time frame

Quantitative analysis of peripheral blood leucocyte subclasses; Expression of markers of antigen presentation; Leucocyte response to activation by stimulatory agents; Leucocyte and whole blood expression of markers of innate immunity inflammatory signaling, including toll-like receptor and inflammasome signaling; Single blood sample from control group; Sequential blood sampling in patients in the first hours after survived cardiac arrest as well as 1 day and 2 days after resuscitation;

—

Countries

Germany

Contacts

Public ContactKatrin Fink

Universitätsklinikum Freiburg / Universitäts-Herzzentrum Freiburg - Bad Krozingen

katrin.fink@uniklinik-freiburg.de004976127034010

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Mar 13, 2026