Clinical study for the evaluation of the effectivity of different tooth brushes in inital treatment of periodontal diseased patients

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00009642

Enrollment

Registered

2016-08-15

Start date

2009-07-01

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

chronical periodontitis K05.3

Interventions

Group 1: oscillating-rotating tooth brush: during the whole study period patients were only allowed to use the oscillating-rotating toothbrush for their daily oral hygiene. At each study related appoi

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: • male/female patients with at least 20 natural teeth • no professional tooth cleaning in the last 6 months • requiring periodontal treatment, i.e., PSI/PSR code 3 and/or 4 in at least 2 sextants • 20% of teeth had a periodontal probing depth (PPD) larger than 4 mm (at least 1 in the maxilla and mandible) • 20% of teeth had attachment loss (CAL)larger than 4 mm • patients with untreated chronic periodontitis and • non-smokers

Exclusion criteria

Exclusion criteria: • Age <18 years • having had an organ transplantation; immune suppression • patients needing endocarditis prophylaxis • patients with infectious disease including hepatitis A, B, C, TBC and HIV • patients with renal insufficiency • patients with neurological and/or cerebral seizure disorders • addicts • patients with known incompatibility/hypersensitivity • pregnancy • patients who underwent antibiotic therapy until 4 months before study start

Design outcomes

Primary

Measure	Time frame
bleeding on probing (BOP), clinical assessment using a periodontal probe (PCP 15, Hu-Friedy, Chicago, IL, USA); evaluation at each investigation appointment.	—

Secondary

Measure	Time frame
modified Quigley-Hein-Index: at each appointment after staining the plaque using erythrosine solution (Mira-2-Ton®, Hager & Werken GmbH & Co. KG, Duisburg, Germany) visually. Papilla Bleeding Index: at each appointment using the periodontal probe (PCP 15, Hi-Friedy, Chicago, IL, USA). recession and periodontal probing depth: at each appointment using the periodontal probe (PCP 15, Hi-Friedy, Chicago, IL, USA). microbiological findings: PCR analysis of 11 periodontal pathogenic bacteria from gingival crevicular fluid samples, which were taken from the deepest periodontal pockets at each appointment.	—

Measure

Time frame

modified Quigley-Hein-Index: at each appointment after staining the plaque using erythrosine solution (Mira-2-Ton®, Hager & Werken GmbH & Co. KG, Duisburg, Germany) visually. Papilla Bleeding Index: at each appointment using the periodontal probe (PCP 15, Hi-Friedy, Chicago, IL, USA). recession and periodontal probing depth: at each appointment using the periodontal probe (PCP 15, Hi-Friedy, Chicago, IL, USA). microbiological findings: PCR analysis of 11 periodontal pathogenic bacteria from gingival crevicular fluid samples, which were taken from the deepest periodontal pockets at each appointment.

—

Countries

Germany

Contacts

Public ContactDirk Ziebolz

Poliklinik für Zahnerhaltung und Parodontologie Universitätsklinikum Leipzig

dirk.ziebolz@medizin.uni-leipzig.de0341-9721211

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026