Extracted tooth roots (rootgrafts) as autogenous transplants for localized alveolar ridge augmentation. A controlled clinical study.

Extracted tooth roots (rootgrafts) as autogenous transplants for localized alveolar ridge augmentation. A controlled clinical study. - rootgrafts

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00009586

Enrollment

Registered

2016-02-10

Start date

2016-02-12

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

localized alveolar ridge defects K08.1 K08.2

Interventions

Group 1: Autogenous tooth roots (retained, impacted teeth) used as autotransplants for localized alveolar ridge augmentation Group 2: Autogenous tooth roots (endodontically treated teeth) used as auto

Eligibility

Sex/Gender

All

Age

18 Years to 60 Years

Inclusion criteria

Inclusion criteria: - Insufficient bone ridge width at the recipient site for implant placement - Sufficient bone height at the recipient site for implant placement - extraction of non-retainable tooth/ teeth (refers to groups receiving autogenous tooth roots) - Healthy oral mucosa, at least 3 mm keratinized mucosa

Exclusion criteria

Exclusion criteria: - Inflammatory and autoimmune disease of oral cavity - Uncontrolled HbA1c (> 7%) in diabetes patients - History of malignancy requiring chemotherapy or radiotherapy within the past five years - Concurrent or previous radiotherapy of head area - Concurrent or previous immunosuppressant, bisphosphonate or high dose corticosteroid therapy - Smokers - Pregnancy or lactating women

Design outcomes

Primary

Measure	Time frame
Clinical width of the alveolar ridge at 26 weeks (calibrated caliper)	—

Secondary

Measure	Time frame
-Soft tissue healing at day 10, week 4, 13, 26, 26 +10 days, 26 + 10 weeks and 26 + 26 weeks (arbitrary scale) -Implant Survival (yes/ no) -Peri-implant indices (i.e. plaque index - PI, bleeding on probing - BOP, probing pocket depth – PD, mucosal recession - MR) at 26 + 10 weeks and 26 + 26 weeks -Immunological analysis of matrixmetalloproteinase- 8 at 26 + 10 weeks and 26 + 26 weeks -Microbiological analyses at 26 + 10 weeks and 26 + 26 weeks	—

Measure

Time frame

-Soft tissue healing at day 10, week 4, 13, 26, 26 +10 days, 26 + 10 weeks and 26 + 26 weeks (arbitrary scale) -Implant Survival (yes/ no) -Peri-implant indices (i.e. plaque index - PI, bleeding on probing - BOP, probing pocket depth – PD, mucosal recession - MR) at 26 + 10 weeks and 26 + 26 weeks -Immunological analysis of matrixmetalloproteinase- 8 at 26 + 10 weeks and 26 + 26 weeks -Microbiological analyses at 26 + 10 weeks and 26 + 26 weeks

—

Countries

Germany

Contacts

Public ContactSara Civale

Poliklinik für Zahnärztliche Chirurgie und Aufnahme, Westdeutsche Lieferklinik, Universitätsklinikum Düsseldorf

Sara.Civale@med.uni-duesseldorf.de0211 81 18272

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Mar 5, 2026