K58
Conditions
Interventions
Group 1: U1: entrance examination with control of the inclusion and exclusion criteria on the basis of medical history, clinical examination and faeces and urine diagnosticss, followed by 2 weeks of t
Sponsors
STZ 1172 Gesundheitsförderung und Stoffwechselforschung
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: -anamnestisch evidence runners diarrhea or GIQLI=112 or irritable bowel symptom of diarrhea type - Age between 18-65 years - Written consent present - Sufficient exercise capacity and regular exercise about 3-4 training sessions / week with a duration of 30-60 minutes at a moderate intensity.
Exclusion criteria
Exclusion criteria: - Presence of disease that affect the gastrointestinal condition or physical fitness (anamnestic or laboratory abnormalities) -Chronic intake of NSAIDs or steroids -Lactose intolerance -Chronic Inflammatory bowel disease -Zoeliakie -Maligne Disease within the last 5 years -antibiotics Therapy in the past 4 weeks - drug addiction - Pregnancy - Food allergy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change in intestinal permeability during physical stress by taking Silicea compared to placebo, which is estimated by the analyzed concentration of Zonulin in the faeces after exercise and test of gastrointestinal permeability (5 hour test) | — |
Secondary
| Measure | Time frame |
|---|---|
| Change in bowel frequency and the change of gastrointestinal quality of life (GQLI) | — |
Countries
Germany
Contacts
Public ContactDenise Zdzieblik
Institut für Sport und Sportwissenschaft
Outcome results
None listed