Cognitive Bias Modification-memory: a computer-based emotional memory training in patients diagnosed with major depressive disorder

Cognitive Bias Modification-memory: a computer-based emotional memory training in patients diagnosed with major depressive disorder - CBMM

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00009459

Enrollment

100

Registered

2015-10-15

Start date

2015-11-04

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

F32 F33

Interventions

Group 1: Cognitive Bias Modification - memory training for positive emotional stimuli. Visit 1: Assessment of primary and secondary outcome measures Visit 2 to 5: 4 x 30 minutes computer aided memory

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Major Depressive Disorder

Exclusion criteria

Exclusion criteria: Major acute psychiatric diseases other than current episode of depressive or mood disorder (for example sleep disorder, psychosis, substance misuse or dependency). Major neurological or other somatic diseases including ischemic or haemorrhagic insults within the subject’s history as well as endocrinologic diseases like thyroid dysfunction, hypercortisolism or adrenal dysfunction. Febrile illness within 3 days before study participation. Severe cognitive impairments and IQ < 70 as estimated by the Mehrfachwahlwortschatztest (MWT-B; Lehrl, 1989).

Design outcomes

Primary

Measure	Time frame
Change in Beck Depression Inventory (BDI-II) scores from visit 1 to visit 5 Time points: visit 1 : Baseline , visit 5 : After the intervention , visit 6 : one week after visit 5	—

Secondary

Measure	Time frame
Change in BDI-Scores at follow-up (one week post training, Visit 5 to Visit 6). The following secondary outcome measures will be assessed for change between visit 1 and visit 5 and between visit 5 and visit 6: Hamilton Depression Rating Scale (HAMD), State Trait Anxiety Scale (STAI), Autobiographical memory (Life Events Questionnaire), Rumination Questionnaire (Response Style Questionnaire), The following secondary outcome measures will be assessed at visit 1 in order to be used as covariates in assessments of treatment changes between visit 1 and visit 5 and visit 5 and visit 6: Cognitive Screening (Syndrom-Kurz-Test, SKT), Estimate of premorbid IQ (Mehrfachwahl Wortschatztests, MWT-B)	—

Measure

Time frame

Change in BDI-Scores at follow-up (one week post training, Visit 5 to Visit 6). The following secondary outcome measures will be assessed for change between visit 1 and visit 5 and between visit 5 and visit 6: Hamilton Depression Rating Scale (HAMD), State Trait Anxiety Scale (STAI), Autobiographical memory (Life Events Questionnaire), Rumination Questionnaire (Response Style Questionnaire), The following secondary outcome measures will be assessed at visit 1 in order to be used as covariates in assessments of treatment changes between visit 1 and visit 5 and visit 5 and visit 6: Cognitive Screening (Syndrom-Kurz-Test, SKT), Estimate of premorbid IQ (Mehrfachwahl Wortschatztests, MWT-B)

—

Countries

Germany, Netherlands

Contacts

Public ContactHannah Windbergs

Klinik für Psychiatrie und Psychotherapie, LVR-Klinikum Essen, Klinik der Universität Duisburg-Essen

hannah.windbergs@lvr.de+49 201 169

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026