inherited cardiomyopathies inherited heart rhythm disturbances healthy probands I42 I45
Conditions
Interventions
Group 1: tissue donation (skin biopsy, peripheral blood, urine) from patients with inherited cardiomyopathies and inherited arrhythmias
Group 2: tissue donation (skin biopsy, peripheral blood, urine)
Sponsors
Zentrum für Physiologie und Pathophysiologie,Institut für Neurophysiologie, Medizinische FakultätUniklinik KölnTel.: (0221) 478-86686Fax: (0221) 478-3834E-mail: tomo.saric@uni-koeln.de
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: - for patients: signed consent form, dilated cardiomyopathy, hypertrophic cardiomyopathy, restrictive cardiomyopathy, arrhythmogenic right ventricular cardiomyopathy, inborn arrhythmias (CPVT, LQTS, Brugada syndrome), legal capacity. - for healthy tissue donors: signed consent form, no known acute or chronic diseases, legal capacity
Exclusion criteria
Exclusion criteria: infectious diseases (HIV, HCV, HBV), disseminated skin diseases or infections, urogenital infections, allergies against local anesthetics (e.g. Lidocain), blood clotting disturbances in test persons without heart diseases, persons in employment contract with the sponsor of the study, involuntary commitment into the mental hospital due to official or judicial order.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Isolation of cells from a skin biopsy, peripheral blood or urine | — |
Secondary
| Measure | Time frame |
|---|---|
| Successful generation of induced pluripotent stem cells (iPS cells) from somatic cells of healthy individuals or patients with inherited heart diseases | — |
Countries
Germany
Contacts
Public ContactTomo Saric
Zentrum für Physiologie und Pathophysiologie,Institut für Neurophysiologie, Medizinische FakultätUniklinik KölnTel.: (0221) 478-86686Fax: (0221) 478-3834E-mail: tomo.saric@uni-koeln.de
Outcome results
None listed