Social interaction and social cognition in borderline personality disorder

Social interaction and social cognition in borderline personality disorder - SOCCOG-IM

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00009429

Enrollment

120

Registered

2015-11-11

Start date

2015-11-17

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

F60.3 F40.1

Interventions

Group 1: Participants perform three different paradigms: Patients with Borderline Personality Disorder 1) Evaluative conditioning paradigm comprising a conditioning and a test phase (Sims et al. 2012

Eligibility

Sex/Gender

Female

Age

18 Years to 55 Years

Inclusion criteria

Inclusion criteria: BPD: = 5 DSM-5 criteria (International Personality Disorder Examination, IPDE) Social Phobia: DSM-5 diagnosis of social anxiety disorder according to Structured Clinical Interview for DSM-IV axis I disorders (SCID)

Exclusion criteria

Exclusion criteria: General exclusion criteria: - Psychotropic medication two weeks prior to investigations - Lifetime diagnosis schizophrenia or bipolar I disorder - Substance dependence within one year prior to study, current substance abuse (verified by negative urine drug screening) - Pregnancy - History of epilepsy, brain trauma, brain tumor, or other significant neurological or medical condition - BMI 2 DSM-IV criteria for BPD (IPDE) Healthy Controls: psychiatric Axis I disorder (SCID); BPD (IPDE)

Design outcomes

Primary

Measure	Time frame
Cerebral activation pattern (BOLD) related to the processing of reward and the association of reward value with social stimuli. Change in activation pattern in the clinical samples should be linked to alterations in neuronal and behavioural correlates of mimicry measured during the test phase of the conditioning paradigm (paradigm 1) and paradigm 2 and 3	—

Secondary

Measure	Time frame
Mimicry in test phase of paradigm 1, as well as in paradigm 2 and 3 measured by error rates, reaction times and EMG activity in response to emotional facial expression Relation between alterations in the processing of reward, the association of reward to social stimuli and mimicry with social functioning (Social Functioning Scale, Birchwood et al. 1990) and psychopathological symptom severity (Borderline Symptomliste (Bohus et al., 2001), UCLA-Loneliness-Questionnaire (Russell et al. 1978).	—

Measure

Time frame

Mimicry in test phase of paradigm 1, as well as in paradigm 2 and 3 measured by error rates, reaction times and EMG activity in response to emotional facial expression Relation between alterations in the processing of reward, the association of reward to social stimuli and mimicry with social functioning (Social Functioning Scale, Birchwood et al. 1990) and psychopathological symptom severity (Borderline Symptomliste (Bohus et al., 2001), UCLA-Loneliness-Questionnaire (Russell et al. 1978).

—

Countries

Germany

Contacts

Public ContactSophie Hauschild

Zentralinstitut für Seelische Gesundheit

sophie.hauschild@zi-mannheim.de0621-17034409

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026