G20
Conditions
Interventions
Group 1: During the five-week intervention period patients of the intervention group will participate in an adaptively designed computerized working memory training. Trainig intensity will be 5 days p
Sponsors
Abteilung für Medizinische Psychologie| Neuropsychologie und Gender Studies Uniklinik Köln
Eligibility
Sex/Gender
All
Age
45 Years to 85 Years
Inclusion criteria
Inclusion criteria: Diagnosis of an ideopathic Parkinson´s syndrome, no cognitve impairment (MDS-Level II-PD-MCI criteria), no dementia, very good German language skills, unimpaired or sufficiently corrected vision and/or hearing ability, signed informed consent
Exclusion criteria
Exclusion criteria: other actual or past neurological disease (besides Parkinson´s disease), deep brain stimulation, actual psychiatric disease, severe depressive symptomes, physical handicap that permits the usage of a computer, diagnosis of a life-threatening disease
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| performance at pre, post and 14-weeks follow-up test within the following domains: verbal working memory (digit span forward (Wechsler Memory Scale-revised; WMS-R), digit span backward (Wechsler Memory Scale-revised; WMS-R), verbal n-Back (Vienna test system; WTS)) and visual working memory (Corsi-Block Tapping forward (Vienna test system; WTS), Corsi-Block Tapping backward (Vienna test system; WTS), nonverbal n-Back (Vienna test system; WTS)) | — |
Secondary
| Measure | Time frame |
|---|---|
| performance at pre, post and 14-weeks follow-up test within the following domains: Disease severity (Unified Parkinson Disorder Rating Scale (UPDRS) motor examination, Scale III), Hoehn & Yahr Stage (UPDRS, Scale V), Depression (Geriatric Depression Scale, GDS-15), Sleep quality (Pittsburgh Sleep Quality Index), subjective cognitive impairment (Subjective Cognitive Impairment-Questionnaire e.g. Every Day Cognition-short version for relatives), Wordlist Learning and Delayed Recall/Recognition (Consortium to Establish a Registry for Alzheimer's Disease, CERAD-Plus), Figure Delayed Recall (CERAD-Plus), Logical Reasoning (Leistungsprüfungssystem; LPS, Subtest 4), Semantical and Phonematical Word Fluency (CERAD-Plus), Mental Flexibility (CERAD-Plus), Inhibition (Stroop Farb-Wort-Interferenz-Test (FWIT), CERAD-Plus), Mental Speed (CERAD-Plus, FWIT), Brief Test of Attention, Mental Rotation (LPS, Subtest 7); performance at pre test within the following domain: self-efficacy (self-efficacy scale); performance across the intervention period (fits only for the intervention group) within the following domain: Motivation (self-constructed questionnaire); neural activity at pre and post test (magnetic resoncance tomography) | — |
Countries
Germany
Contacts
Public ContactAnja Ophey
Abteilung für Medizinische Psychologie | Neuropsychologie und Gender Studies
Outcome results
None listed