B37.0
Conditions
Interventions
Group 1: In clinical routine decontamination of the oral mucosa and prostheses with cold plasma is not performed so far.
In patients with suspected diagnosis of oral candidiasis in the upper jaw, a mi
Sponsors
Charité Campus Benjamin Franklin
Eligibility
Sex/Gender
All
Age
18 Years to 95 Years
Inclusion criteria
Inclusion criteria: Patients eligible for inclusion were able to give informed consent, were between 18 and 95 years old and non-smokers (for =5 years). All patients wore removable prostheses, partially or totally covering the upper alveolar ridge and/or hard palate. Confirmation of diagnosis assumed from clinical signs of infection (at least in terms of erythematous maculae or zones but possibly hyperplasia or complaints as well) via Candida detection was required. Hence, all subjects were diagnosed with denture stomatitis Newton-level 1, 2 or 3 based on both positive clinical and paraclinical findings.
Exclusion criteria
Exclusion criteria: Patients having suffered from any malignant tumor within the last five years or suffering from severe general diseases (American Society of Anesthesiologists (ASA) risk class = 3, myocardial infarction within the last six months, cardiomyopathy, New York Heart Association (NYHA) cardiac insufficiency stage = III, chronic obstructive pulmonary disease (COPD), renal insufficiency, diabetes mellitus (HbA1c = 7%), sickle-cell anemia, rheumatoid arthritis, status post radiation or organ transplantation, malnutrition) were excluded from the study. Furthermore, pacemaker carriers, pregnant women, smokers, alcoholics and drug users were not eligible.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| At the end of treatment after six-time plasma application there is a remission of erythema. The evaluation is carried out using a digital measurement of the photographs made. | — |
Secondary
| Measure | Time frame |
|---|---|
| At the end of treatment after six-time plasma application Candida spp. can not or only sporadically be detected. A mouth swab confirms this. There is a reduction in VAS scores in cases with existing complaints. These are collected once a week. | — |
Countries
Germany
Contacts
Public ContactSaskia Preissner
Charité Campus Benjamin Franklin; CC3 - Zahn-, Mund- und Kieferheilkunde
Outcome results
None listed