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Influence of methylphenidate on sleep-dependent memory consolidation in ADHD

Influence of methylphenidate on sleep-dependent memory consolidation in ADHD

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
DRKS
Registry ID
DRKS00009346
Enrollment
34
Registered
2015-09-10
Start date
2015-10-01
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

F90.0 F90.1 F98.8

Interventions

Group 1: The children spend a total of three nights in the sleep laboratory (consisting of one night to accustom themselves to the new surroundings and two study nights). During all three nights, an E
the second task is a motor skills task. Each morning one pill is administered before and one after learning but only one of the two pills contains the active ingredient. In this group MPH is orally a

Sponsors

Klinik für Kinder- und Jugendpsychiatrie und -psychotherapie, Zentrum für Integrative Psychiatrie, Universitätsklinikum Schleswig-Holstein, Kiel
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
9 Years to 12 Years

Inclusion criteria

Inclusion criteria: ADHD diagnosis, only patients being successfully treated with MPH for at least more than 1 year are included

Exclusion criteria

Exclusion criteria: below-average intelligence, basic memory deficits, sleep disorders, or other psychological disorders

Design outcomes

Primary

MeasureTime frame
The extent of what has been learned (declarative memory task (paired associates learning task) as well as a motor memory task (serial reaction time task) will be measured by an encoding test in the evening. The following night will be spent at the sleep laboratory where sleep will be recorded to compare potential differences in the sleep architecture between the conditions. The recall takes place the next morning, where the retrieval performance is measured as the main outcome.

Countries

Germany

Contacts

Public ContactAlexander Prehn-Kristensen

Klinik für Kinder- und Jugendpsychiatrie und -psychotherapieZentrum für Integrative PsychiatrieUniversitätsklinikum Schleswig-Holstein, Kiel

a.prehn@zip-kiel.de0431 9900 2531

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026