Cognitive Remediation Therapy (CRT) in adults with obesity – a randomised-controlled efficacy trial

Cognitive Remediation Therapy (CRT) in adults with obesity – a randomised-controlled efficacy trial - CRT

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00009333

Enrollment

260

Registered

2015-09-07

Start date

2015-11-26

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

E66.99

Interventions

Group 1: training of executive functions: Cognitive Remediation Therapy (CRT) to support a conservative weight loss programme Group 2: conservative weight loss treatment / Treatment as usual (TAU)

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: •Patients of the IFB AdipositasAmbulanz presentig with obesity grade 2 or 3 (BMI = 35,0 kg/m2) •planned participation in the conservative weight reduction program of the IFB AdipositasAmbulanz •Age = 18 Jahre •Swritten informed consent •sufficient knowledge of the German language •ability to participate in regular appointments at the IFB Studienambulanz

Exclusion criteria

Exclusion criteria: •severe illness (eg neurological diseases, stroke, head injuries) •considerable mental/psychosomatic comorbidity (eg. psychotic disorder, current suicidality, ongoing substance abuse, hyperkinetic disorder, intelligence reduction, developmental disorder) •insufficient compliance •pregnant and nursing women •participation in other interventional trials •ongoing psychtherapy •Physical, metal or other inability to participate in the required tests (eg hearing-, visual or speaking inability) •concomitant medication influencing weight and/ executive functions (eg antipsychotics, sedatives, hypnotics) •previous or planned bariatric surgery

Design outcomes

Primary

Measure	Time frame
Percentual change in weight loss between Baseline (t0) and 6-months-follow-up (t2)	—

Secondary

Measure	Time frame
Changes in the following parameters: (a) exekutiv functions (t0 vs. t1); (b) behavioral indicators for weight loss (t0 vs. t2); (c) compliance with conservative weight loss therapy; (d) mental health (t0 vs. t2); (e) physical health (t0 vs. t2). In addition: changes in these parameters until 12-months follow-up (t3). Weight loss will be analysed in kg. All other parameters will be evaluated using validated tools for •exekutive functions (eg. Iowa Gambling Task) •cognitiven funktions (eg. vigilance (WAFV of the Vienna-Test-System) •behavioral indicators for weight loss (eg. physical activity (IPAQ)) •/validated questionaires for mental health (eg. overall psychopathology (PHQ-D))	—

Measure

Time frame

Changes in the following parameters: (a) exekutiv functions (t0 vs. t1); (b) behavioral indicators for weight loss (t0 vs. t2); (c) compliance with conservative weight loss therapy; (d) mental health (t0 vs. t2); (e) physical health (t0 vs. t2). In addition: changes in these parameters until 12-months follow-up (t3). Weight loss will be analysed in kg. All other parameters will be evaluated using validated tools for •exekutive functions (eg. Iowa Gambling Task) •cognitiven funktions (eg. vigilance (WAFV of the Vienna-Test-System) •behavioral indicators for weight loss (eg. physical activity (IPAQ)) •/validated questionaires for mental health (eg. overall psychopathology (PHQ-D))

—

Countries

Germany

Contacts

Public ContactAnja Hilbert

IFB AdipositasErkrankungenVerhaltensmedizinUniversitätsklinikum Leipzig AöR

ifb@ifb-adipositas.de+49 341 97 15940

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 23, 2026