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Impact of tympanic membrane baroreceptors on Eustachian tube function

Impact of tympanic membrane baroreceptors on Eustachian tube function

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
DRKS
Registry ID
DRKS00009327
Enrollment
20
Registered
2015-09-08
Start date
2015-10-01
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cholesteatoma, acute and chronical tube dysfunction H71 H69.8

Interventions

Group 1: 1. ENT status including examination of the ear and epipharynx 2. Pressure rising and decompression (standardized pressure profile), meanwhile continously measurement of the tympanic impedance

Sponsors

Klinik und Poliklinik für HNO, Kopf- und HalschirurgieKlinikum der Universität zu Köln
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: ear-healthy participants between the age of 18 and 70 years

Exclusion criteria

Exclusion criteria: - pregnancy, - claustrophobia, - exclusion if any operation was done on the ears, - concurrent cold, - inserted grommets or - perforation of the tympanic membrane, - adenoid hypertrophy, - gastroesophageal reflux diseases, and - signs and/or symptoms indicative of active allergic rhinitis.

Design outcomes

Primary

MeasureTime frame
ET opening pressure, ET opening duration, ET opening frequency, and ET closing pressure will be determined before and after local anaesthesia of the tympanic membrane

Secondary

MeasureTime frame
- is a pressure equalization possible (yes/no) - complete or incomplete openings of the eustachian tube during compression or decompression - analysis of pressure progress

Countries

Germany

Contacts

Public ContactMoritz Friedo Meyer

Klinik und Poliklinik für HNO, Kopf- und HalschirurgieKlinikum der Universität zu Köln

moritz.meyer@uk-koeln.de0221-478-4750

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026