TCI Performance after major surgery

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00009312

Enrollment

Registered

2015-09-02

Start date

2015-09-01

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients undergoing surgery in (Propofol-) general anesthesia

Interventions

Group 1: Assessment of propofol Plasma Level at the beginning and at the end of major surgery

Eligibility

Sex/Gender

All

Age

18 Years to 70 Years

Inclusion criteria

Inclusion criteria: Adult patients (18-70 years) undergoing major surgery at the Kantonsspital Frauenfeld in propofol based general anesthesia with intraarterial blood pressure Monitoring according to institutional standard. Major surgery: expected blood loss > 1000 ml (Group 1) or expected duration of surgery > 180 min and expected amount of infusion > 2500 ml (Group 2).

Exclusion criteria

Exclusion criteria: BMI (kg/m2) 35. Allergic to propofol. Emergency surgery. Pregnancy. Known or suspected liver disease.

Design outcomes

Primary

Measure	Time frame
Difference predicted TCI value to real Plasma level	—

Countries

Switzerland

Contacts

Public ContactAlexander Dullenkopf

Institut für Anästhesie und IntensivmedizinKantonsspital Frauenfeld

alexander.dullenkopf@stgag.ch0041-52-7237560

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Mar 4, 2026