The effect of transcranial direct current stimulation on sleep dependent memory consolidation

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00009298

Enrollment

Registered

2015-09-01

Start date

2015-09-28

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy participants

Interventions

Group 1: The healthy participants are introduced into the episodic memory paradigm that can be performed self-guided on a computer. After the learning phase, an immediate recall is carried out. Subseq

Eligibility

Sex/Gender

All

Age

18 Years to 45 Years

Inclusion criteria

Inclusion criteria: 1. Age: 18-45 2. Ability and willingness to participate at the study 3. Ability to give written informed consent 4. Right-handedness 5. A maximum of 5 hours of sleep during the night preceding the study. 6. German (or Swiss German) as mother tongue 7. Normal or corrected to normal vision 8. Females: luteal phase of menstrual cycle

Exclusion criteria

Exclusion criteria: 1. Current or previous neurological or psychiatric disorders, or severe somatic disorders 2. Medical or neurological illness with possible influence on the brain physiology (e.g. arterial hypertension, cardiovascular disease, Morbus Parkinson) 3. Intake of psychotropic medication or psychoactive substances 4. Drug abuse 5. Drug addiction including alcohol within the last two years 6. Pregnancy (pregnancy test will be conducted with every female participant) 7. Current breastfeeding 8. Heart or head surgeries 9. Metal objects on or in the body (e.g. grenade splinter, cardiac pacemaker, vessel clips, metal prostheses, contraceptive coil, cochlear implant, artificial anus with metal cap, hearing aid, tooth implant) 10. Tattoos close to head, neck or shoulder and permanent make-up 11. Claustrophobia 12. Score over 10 at the Epworth Sleepiness scale

Design outcomes

Primary

Measure	Time frame
Memory performance: difference between tDCS and sham tDCS of sleep consolidation, which is the difference between recalled items (grey-scaled faces and associated occupation of the FERET database) before and after sleep	—

Secondary

Measure	Time frame
EEG slow wave amplitude and frequency of occurrence.	—

Countries

Switzerland

Contacts

Public ContactMatthias Grieder

Zentrum für Translationale ForschungUniversitätsklinik für Psychiatrie und PsychotherapieUniversität Bern

grieder@puk.unibe.ch+41319328351

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026