Prospective, controlled, multicenter trial on the prognostic significance of video capsule endoscopy (Capsule Endoscopy) of the small intestine in ulcerative colitis

Prospective, controlled, multicenter trial on the prognostic significance of video capsule endoscopy (Capsule Endoscopy) of the small intestine in ulcerative colitis - CapColitis

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00009235

Enrollment

300

Registered

2015-08-17

Start date

2013-06-04

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

K51

Interventions

Group 1: small intestine capsule endoscopy in patients with ulcerative colitis who were enrolled in the study BioColitis (DRKS00009219)

Eligibility

Sex/Gender

All

Age

18 Years to 80 Years

Inclusion criteria

Inclusion criteria: Ulcerative colitis patients who were enrolled in the study BioColitis (Cu with an early history - enrollment <2 years after initial diagnosis or initiation of a TNF-alpha therapy)

Exclusion criteria

Exclusion criteria: Age at inclusion of small 18 and larger 80 years

Design outcomes

Primary

Measure	Time frame
Incidence of pathological findings in the small intestine of CU patients using video capsule endoscopy (VCE).	—

Secondary

Measure	Time frame
1. predictors and prognostic significance of detectable intestinal changes 2. characterization of factors influencing the natural history of UC 3. Predictive significance of the small intestine changes to therapy need and the therapeutic effect of a TNF-alpha therapy 4. proportion of UC patients with a complicated course (steroid dependency or refractary, proctocolectomy) with a detection of small bowel changes 5. Genetic characterization of CU patients with and without changes in the small intestine using VCE	—

Measure

Time frame

1. predictors and prognostic significance of detectable intestinal changes 2. characterization of factors influencing the natural history of UC 3. Predictive significance of the small intestine changes to therapy need and the therapeutic effect of a TNF-alpha therapy 4. proportion of UC patients with a complicated course (steroid dependency or refractary, proctocolectomy) with a detection of small bowel changes 5. Genetic characterization of CU patients with and without changes in the small intestine using VCE

—

Countries

Germany

Contacts

Public ContactKaren Schmidt

CED Service GmbH

k.schmidt@kompetenznetz-ced.de0431-592 957 5335

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026