Impact of intraoperative target-controlled EEG sedation monitoring on intraoperative vasopressor support in cardiac surgical patients - an interventional trial

Impact of intraoperative target-controlled EEG sedation monitoring on intraoperative vasopressor support in cardiac surgical patients - an interventional trial - NarcoHeart

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00009232

Enrollment

252

Registered

2015-08-19

Start date

2015-10-06

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

I25.0 I08.3

Interventions

Group 1: After written informed consent the day before elective cardiac surgery (with or without CPB) patients will be allocated to undergo anaesthesia either by monitoring of EEG processed sleep dept

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: -planned and elective cardiac surgery with or without CPB - Age >18 years - Written informed consent

Exclusion criteria

Exclusion criteria: - Patient refusal - Allocation to concurrent interventional trials - Clinical staff or relatives - Special operative procedures in hypothermia (i.e. aortic arch operation) - Conceivable CPB time >3h - In case of unforeseeable CBP time >3h or massive intraoperative bleeding, patients will be excluded for final study analysis

Design outcomes

Primary

Measure	Time frame
To evaluate the impact of EEG processed neuromonitoring on intraoperative vasopressor support. Primary endpoint: cumulative intraoperative vasopressor application	—

Secondary

Measure	Time frame
Secondary endpoints focus on (1) intraopoerative fluid administration, (2) intraoperative awareness, (3) time to extubation after surgery, (4) postoperative confusedness and (5) sleep depth between the study arm and control patients	—

Countries

Germany

Contacts

Public ContactChristoph Sponholz

Klinik für Anästhesiologie und IntensivmedizinUniversitätsklinikum Jena

christoph.sponholz@med.uni-jena.de03641 - 9 32 22 25

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026