E75.2 G62.9
Conditions
Interventions
Group 1: Patients with Fabry disease
procedure: proving suitability of the participant, information about the study and procedure in spoken and written form, anamnesis including medical history, neurological examination, questionnaires (
instrument-based examinations: part of quantitative sensory testing (QST) protocol, cold-evoked potenials (CHEPS), heard rate variation test, quantitative cutaneous vasoconstrictor test, skin blood f
same procedure
Group 3: Patients with peripheral neuropathy
same procedure
Sponsors
Universitätsklinikum Schleswig-Holstein Campus Kiel
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Participants have to give their written informed consent. 2. Participants should be able to describe the characteristics including localization and intensity of pain and have the ability to fill out questionnaires 3. Participants need to suffer from pain for at least 3 month because of peripheral neuropathy, multiple sclerosis or Fabry-disease
Exclusion criteria
Exclusion criteria: 1. Alcohol, drug or pharmaceutical abuse (also in history) 2. another disease which can modify sensory signs and symptoms 3. staff or their friends/family of the study team, staff of study hopital 4. simultaneous participation in another study at recruiting visit or within the last 4 weeks
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To find Fabry-specific sensory signs or blood-flow abnormalities, which can segregate to other pain disorders | — |
Secondary
| Measure | Time frame |
|---|---|
| To get hints for the underlying pathomechanism of pain in fabry patients | — |
Countries
Germany
Contacts
Public ContactPaul Möller
Universitätsklinikum Schleswig-Holstein, Campus Kiel, Klinik für Neurologie, Sektion für neurologische Schmerzforschung und -therapie
Outcome results
None listed