No specifications - all tumor patients receiving a mixed infusion with morphine as a result of tumor pain. Loss of effectiveness of morphine in mixed infusions and testing of clinical application.
Conditions
Interventions
Group 1: For patients receiving mixed infusions with morphine and metamizole (either with a syringe pump or analgesic pump), the level of morphine in the blood will be measured as a part of routine bl
Sponsors
Universitätsklinikum Freiburg
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Patients who receive a mixed infusion with morphine as the result of severe pain 2. Opioid-sensitive pain with a fixed opioid dosage 3. Informed patient consent has been given 4. 18 years or older
Exclusion criteria
Exclusion criteria: 1. Intolerance of the medications used 2. History of drug use 3. Radically fluctuating or quickly developing pain symptoms 4. Informed consent is not possible
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Level of morphine in the serum at the beginning and at the end of the mixed infusion | — |
Secondary
| Measure | Time frame |
|---|---|
| Loss of effectiveness in mixed infusions by comparing the concentration of morphine in the infusion with the concentration of morphine in the patients’ serum | — |
Countries
Germany
Contacts
Public ContactGerhild Becker
Universitätsklinikum FreiburgDepartment Innere MedizinKlinik für Palliativmedizin
Outcome results
None listed