Treatment of posttramaumatic stress disorders in patients in in-patient addiction rehabilitation with the EMDR-method - a randomized controlled trial

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

DRKS

Registry ID

DRKS00009007

Enrollment

158

Registered

2016-06-01

Start date

2015-09-09

Completion date

Unknown

Last updated

2025-10-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

F43.1

Interventions

Group 1: Stabilizing PTBS treatment (Treatment as usual) Group 2: Stabilizing PTBS treatment (Treatment as usual) and EMDR

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Substance use disorder according to DSM5 (305.00, 303.90, 291.9); at least subsyndromal PTSD according to DSM5, 309.81 (criteria A and B and at least one more criterion of C to E), assessed with the Clinician Administered PTSD-Scale; patient provided informed consent

Exclusion criteria

Exclusion criteria: Severe dissociative symptomatology (Dissociative Experiences Scale > 40); acute suicidality; acute psychotic symptomatology; severe cognitive impairments

Design outcomes

Primary

Measure	Time frame
PTBS-symptoms, measured by the Clinician Administered PTSD Scale at 6-month-follow-up	—

Secondary

Measure	Time frame
Secondary outcomes 6 months after treatment: PTBS-Symptoms (PTSD Checklist for DSM-5); Alcohol use (mean amount of alcohol per day, number of abstinent days in the last month; Timeline Follow Back); Alcohol /substance use (Alcohol Use Disorders Identification Test; Drug Use Disorders Identification Test); Addiction-related problems (Addiction Severity Index) Depressive symptoms (Beck Depression Inventory II); Dissociative symptoms (Dissociative Experiences Scale); Emotion regulation (Difficulties in Emotion Regulation Scale); Health-related quality of life (Short-Form 12-Item Health Survey)	—

Measure

Time frame

Secondary outcomes 6 months after treatment: PTBS-Symptoms (PTSD Checklist for DSM-5); Alcohol use (mean amount of alcohol per day, number of abstinent days in the last month; Timeline Follow Back); Alcohol /substance use (Alcohol Use Disorders Identification Test; Drug Use Disorders Identification Test); Addiction-related problems (Addiction Severity Index) Depressive symptoms (Beck Depression Inventory II); Dissociative symptoms (Dissociative Experiences Scale); Emotion regulation (Difficulties in Emotion Regulation Scale); Health-related quality of life (Short-Form 12-Item Health Survey)

—

Countries

Germany

Contacts

Public ContactAnnett Lotzin

Zentrum für Interdisziplinäre Suchtforschung (ZIS), c/o Klinik für Psychiatrie und Psychotherapie, Universitätsklinikum Hamburg-Eppendorf

A.Lotzin@uke.de+49-40-7410-55356

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Mar 10, 2026