Physical activity to increase autonomy, cognitive function and health in young people with psychosis (Fit for Life): randomized controlled trial

Physical activity to increase autonomy, cognitive function and health in young people with psychosis (Fit for Life): randomized controlled trial - Fit For Life

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00008991

Enrollment

Registered

2015-08-07

Start date

2015-09-01

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

F20-F29

Interventions

Group 1: The trial will compare two groups: Group 1 (exercise) will be encouraged to exercise 3 x weekly for 12 weeks, for about 1 hour each time. Exercise sessions will be supervised. Different exerc

Eligibility

Sex/Gender

All

Age

18 Years to 45 Years

Inclusion criteria

Inclusion criteria: All persons aged 18-45 years registered as a patient at the Midhagen outpatient unit, with a diagnosed psychotic disorder, who are willing to participate.

Exclusion criteria

Exclusion criteria: Patients with severe somatic disorders, or injuries/risk factors (e.g. muscular-skeletal problems, history of myocardial infarction, etc) that make participation in regular exercise difficult or problematic.

Design outcomes

Primary

Measure	Time frame
Autonomy; assessed at baseline (pre-intervention) and at the final end-point (post-treatment, 12 weeks later), by a clinician-rated questionnaire, the Camberwell Assessment of Need. It includes the following sub-scales: physical health, substance use, social contact, close relationships, psychiatric symptoms.	—

Secondary

Measure	Time frame
Cognitive functioning: assessed by the CogState Brief Battery. Fitness, assessed by the Åstrand V02 sub-max test. Body Mass Index: based on height and weight. Blood samples for tests of HbA1c, fatty acids, inflammatory markers (e.g. IL-6), and epigenetic analyses - will be collected together with the patients ordinary blood tests. From outpatient records: information will be collected on living circumstances, diagnosis, age of onset, medications, somatic disorders, occupation and current sick-leave. Affective responses to acute bouts of exercise will be assessed immediately before and after each training sessions using the PANAS. Each of these assessments will be made at baseline prior to randomization, and again at post-treatment, that is, 12 weeks after baseline assessment.	—

Measure

Time frame

Cognitive functioning: assessed by the CogState Brief Battery. Fitness, assessed by the Åstrand V02 sub-max test. Body Mass Index: based on height and weight. Blood samples for tests of HbA1c, fatty acids, inflammatory markers (e.g. IL-6), and epigenetic analyses - will be collected together with the patients ordinary blood tests. From outpatient records: information will be collected on living circumstances, diagnosis, age of onset, medications, somatic disorders, occupation and current sick-leave. Affective responses to acute bouts of exercise will be assessed immediately before and after each training sessions using the PANAS. Each of these assessments will be made at baseline prior to randomization, and again at post-treatment, that is, 12 weeks after baseline assessment.

—

Countries

Sweden

Contacts

Public ContactYvonne Forsell

Karolinska Institutet

yvonne.forsell@ki.se0728735451

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Mar 3, 2026