complex regional pain syndrome (CRPS)
Conditions
Interventions
Group 1: painful dPNP patients
drawing blood and clinical neurophysiologic investigation
Group 2: non-pain dPNP patients
drawing blood and clinical neurophysiologic investigation
Group 3: posttraumati
Sponsors
European Comission, Directorate - General for Research and Innovationl
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: Patients have to suffer from the diseases of interest. Therefore, patients have to meet minimum diagnostic criteria for CRPS, PNP, nerve lesions, headaches
Exclusion criteria
Exclusion criteria: patients suffering from tumors, acute infection or autoimmune diseases; pregnancy / lactation. Other diseases are registered; but will not prevent patients from participating in the study. This is also applicable for affective disorders. Control subject shall not suffer from any pain disorder, including CRPS, PNP, headaches, as well as traumatic nerve lesions. Patients with pregnancy, breast feeding period or with doubts about compliance will be not included.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary endpoint is to explore the role of ncRNA in chronic pain. Patients data will be explored, the results will be translated into rodent pain models and then backtranslated (confirmed) into patients. | — |
Countries
Czechia, Germany
Contacts
Public ContactFrank Birklein
Klinik und Poliklinik für Neurologie der Universitätsmedizin der Johannes Gutenberg-Universität Mainz
Outcome results
None listed