chronic depression, double depression F34.1
Conditions
Interventions
Group 1: patients receiving CBASP in the mother study now fill out questionnaires concerning current depr. symptomatology and general health
Group 2: patients receiving Escitalopram and clinical manag
Sponsors
Universitätsklinikum FreiburgKlinik für Psychiatrie und Psychotherapie
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: This is a follow-up investigation. Thus only participants of the mother-study were included. The inclusion criteria were as follows: eligible subjects were between 18 and 65 years old and met the DSM-IV criteria for a current episode of chronic major depressive disorder (with the modification of at least 1 year of depressive symptomatology) or recurrent major depressive episodes ( = 3 episodes with the preceding episode no more than 2.5 years before the onset of the current episode). A score of = 18 on the Montgomery-Asberg Depression Scale (MADRS, [24] ) was required. The patients had to be medication free for a minimum of 2 weeks before baseline. Furthermore, the subjects needed to be fluent in German and able to provide written informed consent.
Exclusion criteria
Exclusion criteria: The exclusion criteria were as follows: patients were not eligible for the study if they had an acute risk for suicide (as opposed to suicidal thoughts or chronic suicidality) assessed according to clinical practice guidelines. Further exclusion criteria were: a history of psychotic symptoms, bipolar disorder, or dementia; severe substance- related abuse or dependence disorder; schizotypal, antisocial, or borderline personality disorder; serious medical conditions; severe cognitive impairment, and absence of a response to a previous adequate trial of CBASP or ESC.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| depressive symptomatology after minimum of 2 years after treatment measured via IDS | — |
Secondary
| Measure | Time frame |
|---|---|
| General Health as measured by the WHOWoL-BREF a minimum of 2 years after the mother-study | — |
Countries
Germany
Contacts
Public ContactPaul Bausch
Uniklinikum FreiburgKlinik für Psychiatrie und Psychotherapie
Outcome results
None listed