Cognitive plasticity in middle aged and older adults: Relationships with sociodemographic, clinical and neuropsychological characteristics

Cognitive plasticity in middle aged and older adults: Relationships with sociodemographic, clinical and neuropsychological characteristics - kogplast

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00008875

Enrollment

150

Registered

2015-11-17

Start date

2015-09-21

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy volunteers

Interventions

Group 1: This pilot study examines cognitively healthy participants aged 45 to 80. A neuropsychological test battery, which includes static and dynamic tests. The aim is to find possible relationships

Eligibility

Sex/Gender

All

Age

45 Years to 80 Years

Inclusion criteria

Inclusion criteria: no cognitive impairments, unimpaired hearing and vision

Exclusion criteria

Exclusion criteria: cognitive impairment, uncorrected impairment of hearing or vision, actual psychiatric disease, actual or past neurological disease, 39 years and younger, 81 years and older

Design outcomes

Primary

Measure	Time frame
The primary outcome is cognitive plasticity, i.e the improvement of performance after a cognitive intervention. The following tests are used: - Verbal Learning Memory Potential test (VLMPt) – unpublished german translation (plasticity of verbal memory) - Position Learning Potential test (PLPt) – unpublished german translation (plasticity of nonverbal memory) - Verbal Fluency test (VFt) – unpublished german translation (executive plasticity)	—

Measure

Time frame

The primary outcome is cognitive plasticity, i.e the improvement of performance after a cognitive intervention. The following tests are used: - Verbal Learning Memory Potential test (VLMPt) – unpublished german translation (plasticity of verbal memory) - Position Learning Potential test (PLPt) – unpublished german translation (plasticity of nonverbal memory) - Verbal Fluency test (VFt) – unpublished german translation (executive plasticity)

—

Secondary

Measure	Time frame
The relationship between cognitive plasticity (CP) and sociodemographic factors (age, gender, education), clinical factors (body mass index - BMI), sleep quality (Pittsburgh Sleep Quality Index - PSQI), depression (Becks Depression Index, 5th edition - BDI-V), and subjective memory impairment (Subjective Cognitive Impairment-Questionnaire - SCI-Q)) and performance on neuropsychological tests. The following neuropsychological tests will be used: Mini Mental State Examination (MMSE), Consortium to Establish a Registry for Alzheimer’s Disease (CERAD-Plus), Leistungsprüfungssystem with subtest 4 (LPS 4), subtest 7 (LPS 7) and subtest 9 (LPS 9), Wechsler Memory Scale – revised Version (WMS-R) with subtests „digitspan forward” and „digitspan backwards”, Brief Test of Attention (BTA), Stroop Farb-Wort-Interferenz-Test (Stroop color and word test) with subtests „Farbstrich benennen (color naming)”, „Farbwort lesen (word reading)”, „Interferenzbedingung (interference)”, and Modified Card Sorting Test (MCST).	—

Measure

Time frame

The relationship between cognitive plasticity (CP) and sociodemographic factors (age, gender, education), clinical factors (body mass index - BMI), sleep quality (Pittsburgh Sleep Quality Index - PSQI), depression (Becks Depression Index, 5th edition - BDI-V), and subjective memory impairment (Subjective Cognitive Impairment-Questionnaire - SCI-Q)) and performance on neuropsychological tests. The following neuropsychological tests will be used: Mini Mental State Examination (MMSE), Consortium to Establish a Registry for Alzheimer’s Disease (CERAD-Plus), Leistungsprüfungssystem with subtest 4 (LPS 4), subtest 7 (LPS 7) and subtest 9 (LPS 9), Wechsler Memory Scale – revised Version (WMS-R) with subtests „digitspan forward” and „digitspan backwards”, Brief Test of Attention (BTA), Stroop Farb-Wort-Interferenz-Test (Stroop color and word test) with subtests „Farbstrich benennen (color naming)”, „Farbwort lesen (word reading)”, „Interferenzbedingung (interference)”, and Modified Card Sorting Test (MCST).

—

Countries

Germany

Contacts

Public ContactSarah P. Rehberg

Uniklink Köln, Abteilung Medizinische Psychologie

sarah.rehberg@uk-koeln.de0221/47896247

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026