Neural circuits involved in phantom limb pain

Neural circuits involved in phantom limb pain - SFB_PLP

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00008842

Enrollment

295

Registered

2017-07-11

Start date

2015-10-01

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Phantom Limb Pain

Interventions

Group 1: Magnetic Resonance Imaging (MRI), Transcranial Magnetic Stimulation (TMS), electroencephalogram (EEG), Quantitative Sensory Testing (QST), Peripheral Nervous Stimulation (PNS), coginitive tes

Eligibility

Sex/Gender

All

Age

18 Years to 75 Years

Inclusion criteria

Inclusion criteria: Patients with amputation, or patients who are going to be amputated or participants with dysmelia.

Exclusion criteria

Exclusion criteria: Neuropsychiatric diseases, dementia, missing legal capacity

Design outcomes

Primary

Measure	Time frame
Factors that influence the development of phantom pain will be assessed using functional neuroimaging and electroencephalographie. Influencing factors are psychological states before amputation and cortical excitability as measured using transcranial magnetic stimulation (2015-2019).	—

Secondary

Measure	Time frame
Potential for therapies for chronic pain. Identification of cortical targets involved in phantom pain will be modulated using combined transcranial magnetc stimulation and neuroimaging.	—

Countries

Germany

Contacts

Public ContactAstrid Wolf

Zentralinstitut für Seelische Gesundheit Institut für Neuropsychologie und Klinische Psychologie

astrid.wolf@zi-mannheim.de0621/1703-6344

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026