I21
Conditions
Interventions
Group 1: Interventional Study-proved Strategy (BIC-8) (DRKS-ID: DRKS00000276) using Copeptin and Troponin for the Early Rule-Out of Acute Myocardial Infarction (AMI) in Patients with Suspected Acute
Sponsors
Rettungsstellen Campi Nord Internistische Notaufnahme CVK
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: • Admission to the Emergency Department or CPU with signs and symptoms consistent with acute coronary syndrome • Low-to intermediate risk profile (GRACE-score below 140 and a low- to intermediate likelihood of ACS as judged by the treating physician) • Patients eligible for the early rule-out strategy using combined copeptin and troponin testing at admission, irrespective of biomarker test results and disposition decision • full-aged patient
Exclusion criteria
Exclusion criteria: None
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Primary objective: •One-month all-cause mortality in patients in whom acute myocardial infarction is ruled-out using the early rule-out strategy and who are therefore discharged from the ED. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary objectives in all patients tested for copeptin and troponin at admission, irrespective of biomarker test results and disposition decision: • Diagnosis of acute myocardial infarction • Final hospital diagnoses • Time to discharge/transfer from the ED/CPU • Disposition decision (discharge or admission) • Length of hospital stay • ICU-treatment • Performance of Coronary angiography/ PCI/ CABG • Performance of ECGs, stress testing, imaging • Performance of cardiovascular monitoring • In-hospital mortality • One-month mortality | — |
Countries
Austria, France, Germany, Hungary, Lithuania, Switzerland, Turkey, United Kingdom
Contacts
Public ContactAnna Slagman
Rettungsstellen Campi Nord Internistische Notaufnahme CVK
Outcome results
None listed