Molecular and histopathological examinations of adhesions in patients with posttraumatic syringomyelia

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00008584

Enrollment

Registered

2015-08-21

Start date

2015-09-01

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

G95.0 G82

Interventions

Group 1: Spinal cord injured patient, who require adhesiolysis due to rapid ascending neurologic deficits (analysis of subarachnoid scarring tissue, serum and CSF) Group 2: Control group (patients who

Eligibility

Sex/Gender

All

Age

18 Years to 80 Years

Inclusion criteria

Inclusion criteria: - prior spinal cord injury - development of posttraumatic syringomyelia

Exclusion criteria

Exclusion criteria: - Syringomyelia related to other causes (Arnold Chiari, postinfectious etc.) - absent informed consent

Design outcomes

Primary

Measure	Time frame
Displaying histopathological hallmarks of syringomyelia (TGF-beta and pathway mediators in histology, CSF and serum)	—

Secondary

Measure	Time frame
identification of other molecular risk factor for posttraumatic syringomyelia (in Serum or CSF, or other than TGF-ß).	—

Countries

Germany

Contacts

Public ContactLukas Grassner

Center for Spinal Cord Injuries, BG Trauma Center Murnau, Germany

lukas.grassner@bgu-murnau.de00498841484864

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026