M16.1 K40.9
Conditions
Interventions
Group 1: General anaesthesia will be performed by total intravenous anaesthesia (TIVA) using propofol and the opiate remifentanile in combination with measurement of depth of anaesthesia by electroenc
Sponsors
Park-Klinik WeissenseeAbteilung Anästhesiologie Intensivmedizin
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Patients undergoing elective surgery under general anaesthesia Endotracheal intubation Minimum age of 18 years ASA-classification I-III Minimum duration of operation 30 minutes Good knowledge of German for understanding
Exclusion criteria
Exclusion criteria: Lack of willingness to accept storage and transfer of pseudonymised health data Emergency surgery Pregnancy Inoperable regarding the ASA-classification Artificial ventilation postoperatively Lack of an informed consent Age under 18 years Participation in an other study during the last three month Mental disorders History of an adverse reaction to study medication
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| prevalence and severity of PONV (acquired by postoperative questionnaire, day of surgery, first and second postoperative day) | — |
Secondary
| Measure | Time frame |
|---|---|
| sevoflurane concentration( Vol%exp) at a given depth of anaesthesia (Narcotrend-signal: D2-E0) and a fix propofol dosage (1 µg/ml, TCI-modus) [intraoperative measurement] use of vasoactive substances such as norepinephrine [intraoperative measurement and recovery room] pain level and need in analgesics postoperatively [recovery room, day of surgery, first and second postoperative day] duration of stay in recovery room [postoperative measurement] cognitive function [1 day preoperatively, recovery room, first and second postoperative day] | — |
Countries
Germany
Contacts
Public ContactMario Hensel
Park-Klinik WeissenseeAbteilung Anästhesiologie Intensivmedizin
Outcome results
None listed