Recognition of Sleep Apnea by Analysis of the Routine Holter ECG - Pilot Study with Exploratory Data Analysis

Recognition of Sleep Apnea by Analysis of the Routine Holter ECG - Pilot Study with Exploratory Data Analysis - Carrera (CARdiac REspiratory RAdar)

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00008567

Enrollment

200

Registered

2015-09-03

Start date

2014-10-30

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

G47.3 R06.3 E66.2

Interventions

Group 1: Patients who are scheduled for a Holter ECG recording owing to their medical history, will receive a polygraphy device upon inclusion to the study. It will be used to monitor nocturnal respir

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients who are scheduled for a Holter ECG registration by the Heidelberg University Hospital. Patients must be able to attach polygraphy sensors and activate the pholygraphy device.

Exclusion criteria

Exclusion criteria: none

Design outcomes

Primary

Measure	Time frame
The reference value for the severity of a sleep related breathing disorder will be the apnea-hypopnea index (AHI) as assessed from the polygraphy. An exploratory data analysis will identify the suitability of ECG parameters for robust detection of sleep apnea, and the level of sensitivity and specficity that can be expected from analysis of routine Holter ECG recordings. Moreover, the prevalence of sleep apnea in a routine Holter ECG collective will be estimated.	—

Measure

Time frame

The reference value for the severity of a sleep related breathing disorder will be the apnea-hypopnea index (AHI) as assessed from the polygraphy. An exploratory data analysis will identify the suitability of ECG parameters for robust detection of sleep apnea, and the level of sensitivity and specficity that can be expected from analysis of routine Holter ECG recordings. Moreover, the prevalence of sleep apnea in a routine Holter ECG collective will be estimated.

—

Secondary

Measure	Time frame
The possibility to specifically identify respiratory events of central origin from the routine Holter ECG, and the impact of concomitant factors like comorbidity or medication on the detectability of sleep related breathing disorders from the Holter ECG	—

Countries

Germany

Contacts

Public ContactJörg Friedrich

Medizinische Klinik (Krehl-Klinik), Abteilung Innere Medizin III (Kardiologie, Angiologie und Pneumologie)

Joerg.Friedrich@med.uni-heidelberg.de+49 (0)6221/56-38672

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026