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Respiratory mechanics and ventilation using controlled expiration (FLEX) in lung-healthy adults during elective surgery with general anesthesia.

Respiratory mechanics and ventilation using controlled expiration (FLEX) in lung-healthy adults during elective surgery with general anesthesia. - FlexOP-EIT

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
DRKS
Registry ID
DRKS00008555
Enrollment
30
Registered
2015-06-05
Start date
2015-06-09
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

perioperative artificial ventilation

Interventions

Group 1: Application of positive endexpiratory pressure (PEEP) of 7mbar only for 5min calibration + 20min measurements, then application of positive endexpiratory pressure (PEEP) of 5mbar with contro

Sponsors

Universitätsklinikum Freiburg
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: adults of at least 18 years of age, informed written consent, elective surgery, artificial ventilation

Exclusion criteria

Exclusion criteria: known pulmonary disease, cardiac pacemaker, automated implantable cardioverter-defibrillator or other active implants, heart defects, laparoscopic surgery

Design outcomes

Primary

MeasureTime frame
Perioperative non-linear intratidal compliance, continously measured [ml/mbar] from the end of induction until the end of the surgery

Secondary

MeasureTime frame
Continuously measured perioperative regional ventilation (using EIT (electrical impedance tomography) - pixel) as well as Oxygenation (SaO2, PaO2), drawn from standard-monitoring, from the end of induction until the end of the surgery

Countries

Germany

Contacts

Public ContactSteffen Wirth

Klinik für Anästhesiologie und Intensivmedizin Universitätsklinikum Freiburg

steffen.wirth@uniklinik-freiburg.de+49761270240101

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026