Changes of the gastrointestinal microbiome in perioperative patients

Changes of the gastrointestinal microbiome in perioperative patients - GIMA-Trial

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00008535

Enrollment

150

Registered

2015-10-28

Start date

2015-11-01

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

A41 C25 Z98

Interventions

Group 1: Stool samples for a 16S RNA analyse and also all relevant clinical data will be collected in 150 patients undergoing a whipple operation at the time points preoperative, 1d, 3d, 5d, and 7d. A

Eligibility

Sex/Gender

All

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: *Written consent form of study participant or his appointed representative *Age > 18 years *undergoing a whipple-operation

Exclusion criteria

Exclusion criteria: *Non-fulfillment of inclusion criteria *chronic inflammatory diseases *antibiotic allergies *Refusal of participation in the study

Design outcomes

Primary

Measure	Time frame
Changes in the gastrointestinal microbiome under antibiotic therapy (stool samples: preoperative, 1d, 3d, 5d, 7d) Comparison of the microbiome changes and clinical complications (preoperative, 1d, 3d, 5d, 7d)	—

Secondary

Measure	Time frame
*Comparison of the micobiome changes and outcomerelevance at the timepoints: preoperative, 1d, 3d, 5d, 7d (addditionally: reevaluation: 28d, 90d)	—

Countries

Germany

Contacts

Public ContactFelix Carl Fabian Schmitt

Universitätsklinikum HeidelbergKlinik für Anästhesiologie

felix.schmitt@med.uni-heidelberg.de06221-56-39421

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026